Bridging raw agricultural sourcing with ultra-high purity molecular isolation for global industrial application.
The global demand for premium berry-derived botanical extracts, specifically from high-quality Rubus idaeus (Raspberry) sources, has undergone a structural paradigm shift. No longer limited to functional flavorings, industrial sectors ranging from dietary supplements and metabolic therapeutics to clean-label cosmetic formulations are requiring standardized molecular markers, such as Raspberry Ketone (4-(4-hydroxyphenyl)butan-2-one), anthocyanins, and ellagitannins.
As a leading pharmaceutical-grade ingredient manufacturer, UniCare offers vertically integrated supply chains that secure raw agricultural inputs and utilize state-of-the-art multi-functional extraction systems. Our operations maintain precise control over temperature, pressure, and solvent ratios to guarantee maximum retention of volatile bioactives.
By establishing rigorous agricultural controls (GACP) and processing limits, we eliminate common raw material variables such as heavy metal uptake, pesticide contamination, and batch-to-batch component degradation. This provides international formulation brands with absolute security and unmatched performance consistency.
Annual Raw Processing Capacity
Net Profit Invested in R&D
Multifunctional Extraction Lines
Certified Central Laboratory
Adapting clean botanical science for localized applications across key business verticals.
Active natural compounds derived from premium raspberry extracts serve as highly effective catalysts in lipid metabolism formulations. Standardized raspberry ketone profiles are integrated globally into weight management therapeutics and sports nutrition formulations to enhance adiponectin secretion, driving lipid oxidation pathways without central nervous system stress.
Rich in polyphenols, superoxide dismutase (SOD) equivalents, and ellagic acid, our botanical extracts function as superior radical-scavenging actives. They protect skin cells from UV-induced oxidative stress, inhibit melanogenesis pathways, and support dermal structural integrity in premium cosmetics.
As consumer preferences shift away from synthetic additives, our high-purity botanicals like Stevia and clean berry extracts enable sugar reduction and nutritional enrichment. We preserve natural antioxidant properties, ensuring clean sensory profiles and clean-label integrity.
Driving global health innovation through persistent scientific R&D and strict ecological stewardship.
UniCare attaches great importance to the hardware conditions of production equipment and operates the largest and most advanced extraction factory in China. The entire production line is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops containing six multi-functional extraction lines, among which is the only production line for Ginkgo Biloba Extract of acetone process in the whole of China. Here are several other production lines, including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
All operations and management steps in our facility strictly follow current GMP regulations to ensure batch compliance.
Our Ginkgo Biloba extraction line meets rigorous EU-GMP standards, proving our processes satisfy Western monograph requirements.
Real-time distributed control systems (DCS) stabilize physical conditions, avoiding processing deviations during production runs.
Six automated lines: Three annular dynamic countercurrent lines (10T & 15T); two multi-functional lines (32 tanks, 6 cubic meters each); one round countercurrent line (10T).
Analytical precision testing ensures absolute safety and chemical verification for every single batch.
| Quality Control Category | Testing Details & Monitored Parameters |
|---|---|
| Active Ingredient Analysis | Assay verification, HPLC/UV chemical profile fingerprinting, and identity testing. |
| Hazardous Substance Analysis | ICP-MS heavy metals, GC-MS-MS multi-pesticide screens, and residual solvent detection. |
| Microbiological Analysis | Total plate count, yeast & mold, E. coli, Salmonella, and specific pathogen testing. |
| Raw Material Control | GACP botanical origin verification, moisture limits, ash evaluation, and GMO screening. |
| Regulatory Compliance | Global regulatory verification (FDA, EFSA, CFDA) for cross-border customs compliance. |
| Stability Analysis | Accelerated and long-term shelf-life studies in environmental chambers. |
Our centralized testing lab spans a wide analytical footprint and is fully qualified under CNAS (ISO/IEC 17025) certification. This setup guarantees that testing reports are internationally recognized. We evaluate signature constituents, pesticide residues (via GC-MS-MS), heavy metals (lead, arsenic, mercury, cadmium, copper via ICP-MS), residual solvents, microbiological levels, moisture, density, and physical particle sizes.
By operating these systems in-house rather than relying solely on third-party labs, we maintain complete control over quality validation timelines and chemical analysis parameters.
Two sets of ultra-high performance liquid chromatography systems for rapid active ingredient fingerprinting.
Four sets of high-performance liquid chromatography systems for stable and routine quantitative analysis.
High-resolution gas chromatograph used to detect residual extraction solvents and pesticide profiles.
Atomic absorption system used for heavy metal quantification down to parts-per-billion (ppb) levels.
Pushing scientific boundaries in natural fermentation while securing agricultural supply chains at the source.
UniCare reinvests 10% of our annual net profit directly back into our research and development department. Beyond optimizing traditional chemical solvent extractions, we run a dedicated division focused on natural microbial fermentation processes.
We work in deep collaboration with the Beijing University of Chemical Technology in industrial fermentation. This partnership helps us transition new active pharmaceutical, cosmetic, and nutritional compounds from laboratory pilot stages into large-scale production.
To control agricultural variables, we have built a procurement and tracing system that links each production batch back to its original cultivation site. Raw materials are checked for active marker compounds, moisture, ash, and pesticide residues upon arrival.
Additionally, we work directly with farming cooperatives to run dedicated cultivation bases for Ginkgo, Epimedium, Phellodendron, and Olive Leaf. Some of these bases follow the GACP (Good Agricultural and Collection Practices) framework, utilizing genetic cultivation techniques to increase yield and reduce downstream unit costs.
Pioneering clean-label extraction processes while meeting global regulatory frameworks.
Our long-term engineering roadmap focuses on adopting green chemistry technologies. This includes shifting target extractions to Supercritical Carbon Dioxide (sCO2) and subcritical water extraction systems. These methods minimize organic solvent use, eliminate toxic residues, and preserve volatile bioactive components, allowing us to supply clean-label ingredients for global brands.
In addition, we continue to scale up our industrial fermentation capacity. By utilizing genetically optimized microbial hosts and enzyme-modified bioconversions, we aim to produce rare secondary metabolites—such as specific minor cannabinoids, rare ginsenosides, and highly bioavailable polyphenols—more sustainably and cost-effectively than traditional farming.
Recognizing the complex regulatory environment across major regions, UniCare operates a dedicated regulatory affairs division. We help clients navigate compliance challenges, assisting with FDA New Dietary Ingredient (NDI) notifications, EFSA Novel Food approvals, China cosmetic ingredient registrations, and Kosher and Halal certifications. This comprehensive support ensures smooth custom clearances and rapid market entry for your products.
Clear answers regarding sourcing, regulatory compliance, and industrial botanical extraction.
A quality supplier must offer complete traceability (GACP-compliant sourcing), standardized active compound percentages verified by HPLC, and low heavy metal/pesticide counts (using ICP-MS and GC-MS-MS). They should also operate under certified GMP conditions to prevent cross-contamination.
We conduct real-time and accelerated stability trials in environmental chambers to monitor active compounds under various temperature and humidity profiles. This data allows us to establish accurate expiration dates and recommend optimal storage conditions.
The acetone process is a primary pharmaceutical extraction standard for Ginkgo Biloba. It selectively isolates beneficial terpene lactones and ginkgoflavone glycosides while keeping harmful ginkgolic acids under the strict 5 ppm threshold mandated by EU-GMP and European Pharmacopoeia standards.
Partnering with the Beijing University of Chemical Technology allows us to deploy advanced enzymatic and industrial fermentation processes. This increases extraction yields, reduces raw material waste, and helps lower unit manufacturing costs for our customers.
Get in touch with our technical sales engineers to request HPLC chromatograms, certificate of analyses (CoA), samples, or custom formulation quotes.
