Explore our premium selection of botanical extracts supplied globally under strict GMP and international regulatory standards.
In the modern global supply chain for natural APIs and high-purity phytochemicals, Rutin has emerged as an indispensable cornerstone raw material. As a crucial bioflavonoid extracted predominantly from the flower buds of Sophora japonica L. (the Chinese scholar tree), Rutin serves as a direct precursor to several essential therapeutics and advanced dietary ingredients, including Quercetin, Troxerutin, and various enzyme-modified flavonoids. Large-scale procurement teams in the pharmaceutical, cosmetic, and nutraceutical industries require not only volume stability but rigorous compliance with pharmacopoeia standards (USP, EP, DAB, BP).
Global demand is driven by the clinical recognition of Rutin's capacity to reduce capillary permeability, support venous health, combat cellular oxidation, and modulate inflammatory pathways. For instance, European pharmaceutical giants utilize large volumes of highly purified Rutin to synthesize Troxerutin, which is globally prescribed for chronic venous insufficiency (CVI) and varicose syndrome. Concurrently, the global functional beverage and cosmetic sectors are shifting toward highly soluble bioflavonoids, creating unique needs for micronized, anhydrous, and custom-granulated Rutin forms.
How China's leading extraction infrastructure optimizes cost, quality, and supply continuity.
By operating our own Sophora japonica planting bases, we mitigate the risk of harvest volatility. This direct agricultural vertical integration ensures stable raw material pricing and consistent quality year-round, insulating our global clients from spot-market price spikes.
Recognizing the diverse formulation challenges faced by solid dosage and liquid manufacturers, we offer customized milling, micronization (<10 μm), and direct compression (DC) granulation to improve flowability and dissolution properties.
We supply comprehensive technical documentation to streamline international registrations, including Active Substance Master Files (ASMF) / Drug Master Files (DMF), Kosher/Halal certifications, and full allergen declaration matrixes.
Solidifying our role as a major partner in global botanical extract production.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Unlocking natural bioactives to create value for human health products globally.
Evolving our processing, purification, and standardization steps every year.
Deploying state-of-the-art extractors to produce elite, standardized, high-yield plant fractions.
Supporting our farmers and workforce, fostering ecological sustainability and shared growth.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The factory has passed the China GMP certification: Ensuring consistent manufacturing environment control and strict process documentation.
The EU-GMP and CEP of Ginkgo Biloba Extract has been certificated: Demonstrating our capability to satisfy Europe's highest pharmaceutical-grade botanical drug thresholds.
All extraction production lines adopt modern, intelligent and automated control systems: Minimizing human error and ensuring high batch-to-batch repeatability of bioactive concentration.
Own the most advanced extraction equipment in China: Integrated with computerized process parameters, optimizing extraction rates of active substances.
Annual processing of 30,000 tons of Chinese medicine and plant raw materials: Offering stable, massive supply scalability to large-scale international distributors.
Six dedicated extraction lines: Three annular dynamic countercurrent extraction lines (10 tons & 15 tons); two multi-functional extraction lines (32 extraction tanks with six cubic each); one round dynamic countercurrent extraction line (10 tons).
Only acetone process extraction line for Ginkgo Biloba Extract in China: Fully engineered to align with stringent EU-GMP standards.
Six fermentation tanks (20 tons capacity each): Dedicated to the precision production of advanced enzyme-modified botanical and flavonoid derivatives.
Visual verification of our large-scale, cleanroom extraction complexes and processing plant.
The global bioflavonoid market is shifting away from simple extraction processes toward molecular optimization. Historically, raw Rutin was extracted using a traditional hot water reflux or basic alkaline-acid precipitation. While this method yields standard Rutin powder, it often carries high water-insolubility, low bioavailability, and risk of solvent residues. UniCare’s current technical roadmap addresses these bottlenecks directly.
Our collaborative projects with the Beijing University of Chemical Technology explore green, enzymatic routes that utilize natural biocatalysts to transform Rutin into high-value modifications. Foremost among these is Alpha-Glycosylrutin, which possesses up to 12,000 times higher water solubility than raw Rutin, making it highly valuable for premium cosmetic formulations and clear liquid nutraceutical formulations. Additionally, our R&D focus is moving toward enzymatic synthesis of Troxerutin (hydroxyethylrutoside) with high purity and minimal environmental footprint.
To control active content right from the soil, we collaborate with leading botanical institutes to cultivate high-yield Sophora japonica strains. These hybrids demonstrate a 20-30% higher native concentration of bioflavonoids than wild types, effectively reducing baseline extraction cost and environmental footprint.
Investing 10% of our annual net profit back into biotechnology, we developed continuous enzyme-modification lines. By using specialized enzymes, we can break down rutinose glycone complexes, tailoring specific bioflavonoid structures with heightened pharmacokinetics.
UniCare operates a CNAS-qualified central laboratory utilizing world-class instrumentation to validate every critical quality attribute.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, we provide every customer with high-grade active ingredients. Detectable items include signature component assay (HPLC or UV), solvent residues (GC), pesticide residues (GC-MS-MS for organochlorine detection), heavy metals (lead, arsenic, mercury, cadmium, copper by ICP-MS), microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer chromatography (TLC) identification, and routine tests (pH, conductivity, sulfur dioxide residue).
Our central laboratory contains key analytical hardware:
| Quality Control Domain | Specific Testing Parameters & Targets |
|---|---|
| Active Ingredient Analysis | Assay (HPLC validation vs. USP/EP standard), TLC identification, UV peak verification. |
| Hazardous Substance Analysis | Heavy metals (Pb, As, Hg, Cd, Cu) via ICP-MS; multi-residue pesticide screen (EP/USP standards); residual solvents (methanol, ethanol, acetone). |
| Microbe Analysis | Total aerobic microbial count (TAMC), total combined yeasts and molds count (TYMC), Escherichia coli, Salmonella, and specific pathogens. |
| Raw Material Control | Sophora japonica botanical authentication, moisture testing, GACP cultivation site pesticide trace limits, GMO screening. |
| Laws & Regulations Confirmation | Validation against Pharmacopoeia monographs (USP, EP, ChP), EU Food Additive limits, US FDA GRAS compliance. |
| Stability Test | Accelerated and long-term climate chamber stability runs to guarantee shelf life under varying zones. |
| Physical/Chemical Routine | pH value, moisture content, total ash, bulk/tapped density, particle size analysis (laser diffraction), optical rotation. |
Spanning a large footprint, our Central Lab is qualified by CNAS. It is staffed by senior PhD researchers and phytochemistry technicians. The analytical instrumentation includes:
| Instrument Type | Manufacturer & Model | Quantity |
|---|---|---|
| UHPLC (Ultra High Performance Liquid Chromatograph) | Agilent 1290 | 2 Units |
| HPLC (High Performance Liquid Chromatograph) | Agilent 1260 / Shimadzu LC-20AT / Dionex CU3000 | 8 Units |
| ELSD (Evaporative Light Scattering Detector) | Shimadzu 2000ES | 2 Units |
| GC (Gas Chromatograph) | Shimadzu GC-2010 | 1 Unit |
| AAS (Atomic Absorption Spectrophotometer) | Shimadzu AA-7000 | 1 Unit |
Securing raw material purity from planting seeds to advanced molecular extraction.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction processes, we have established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through traditional processes and disrupt the industry development model. We work in deep cooperation with the Beijing University of Chemical Technology in the field of fermentation, developing and transforming new raw materials for pharmaceutical, cosmetic, and natural health products into mass-produced products.
To control raw materials efficiently and with higher quality, we have established a raw material procurement system extending directly to our planting lands, allowing full traceability for each batch. Raw material storage complies with our advanced quality management processes, strictly controlling active ingredient content, moisture, ash, heavy metals, and pesticide residues.
To ensure high quality, UniCare cooperates with planting farmers to establish Ginkgo leaf, Epimedium, Phellodendron, and Olive leaf planting bases. Some of these bases are managed strictly under the GACP (Good Agricultural and Collection Practices) model. Additionally, we collaborate with seedling R&D companies to develop high-content cultivars via hybridization or genetic optimization, reducing unit costs to benefit our clients.
In B2B active ingredient sourcing, product quality is only half the battle. Regulatory compliance is the actual gatekeeper. At UniCare, we design our systems to ensure your regulatory filings progress smoothly. Our team of compliance experts monitors changes in international pharmacopoeia standards (USP, EP, DAB, JP) and regional contaminant limits to ensure our Rutin and other active ingredients align with current specifications.
Whether you require standard 95% NF11 Rutin or specialized EP-compliant Rutin, our technical team provides documentation including detailed certificates of analysis (CoA), allergen matrices, TSE/BSE free declarations, GMO statements, and residual solvent reports. Additionally, our logistics framework supports container shipping, custom packaging, and warehousing to ensure delivery to your production facilities worldwide.
Technical and logistical insights to help procurement managers and formulation chemists source Rutin effectively.
Discover our comprehensive range of standardized phytomedicinal raw materials.
