Advanced standard botanical extracts from our GMP-certified manufacturing complex.
Mitochondrial health is the core engine of metabolic and cellular longevity. While traditional Berberis extracts (Standard Berberine HCl) have served as potent natural AMPK activators, their industrial and clinical utility has long been bottlenecked by poor gastrointestinal absorption and low relative cellular bioavailability.
Doctor Mito Berberis represents the paradigm shift. Utilizing state-of-the-art phytochemical science and molecular delivery platforms, Doctor Mito Berberis is engineered to target the mitochondrial membrane directly. By enhancing intracellular accumulation and molecular stability, our optimized Berberis extract provides up to 5x metabolic efficacy at standard dosages.
As global dietary supplement markets transition toward precision longevity, functional food manufacturers, healthcare professionals, and supplement brands are sourcing Doctor Mito Berberis to formulate next-generation insulin-sensitivity, cognitive-enhancement, and cellular-rejuvenation solutions.
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UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Through our vertically integrated supply chain, we bridge the gap between agrarian botanical cultivation and high-technology pharmaceutical applications.
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Guiding our innovation, technology, sustainable development, and social commitments.
We combine ancient biological wisdom with modern biochemical synthesis to discover untapped properties within botanical sources.
Rethinking extraction ratios, solvent-free applications, and environmental impact controls in every refinement cycle.
Utilizing high-performance chromatography and automated dynamic countercurrent systems for batch purity consistency.
Fostering cooperative local agricultural networks, paying fair wages, and funding green cultivation programs.
Critical data, application scenarios, and biological trends defining the metabolic supplement sector.
The demand for Doctor Mito Berberis has experienced an exponential compound annual growth rate (CAGR) of 18.2% over the last four years. In North America and Europe, consumers are actively seeking natural alternatives to synthetic metabolic modulators. As clinical researchers continue to publish data supporting mitochondrial biogenesis and glucose disposal pathways, large-scale industrial buyers are securing long-term export allocations from China's primary extraction factories.
To maximize market adoption, Doctor Mito Berberis is formulated across multiple delivery vectors:
Our 5-year technical roadmap focuses on the absolute elimination of chemical solvent residues through clean green technology. By developing enzymatic bioconversion steps and advanced structural phytosome carriers, UniCare plans to launch water-soluble Doctor Mito Berberis variants that can seamlessly integrate into standard functional drinks and carbonated beverages without precipitation.
UniCare acts as a comprehensive raw ingredient partner. Beyond supply, we provide regulatory assistance (FDA, NDI notifications, EFSA compliance documentation), custom assay standardization (customizing Berberis content up to 99% purity), and complex custom blending services for brands requiring tailored metabolic health formulations.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
Our factory operation strict complies with domestic and international GMP frameworks.
EU-GMP and CEP certifications achieved for Ginkgo Biloba Extract processes.
Modern digital orchestration monitoring temperatures, pressure and yields in real-time.
Utilizing highly efficient machinery that respects natural volatile compounds.
Sufficient industrial scale to supply bulk global botanical markets consistently.
Three annular dynamic countercurrent (10/15T), two multi-functional, one round dynamic.
The only plant line in China conforming strictly to European Ginkgo Biloba standards.
Six specialized fermentation tanks (20 tons capacity each) for optimized enzyme conversions.
An inside look into our processing, refining, structural characterization and storage facility.
Guaranteeing molecular fingerprint consistency, safety, and strict regulatory adherence.
Detectable items are: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Important testing instruments are: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, there are two HPLC Shimadzu LC-20AT high performance liquid chromatograph, two HPLC Diane CU3000, two Shimadzu evaporative light scattering detector 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
| Quality Control Target | Testing Items & Action Protocols |
|---|---|
| Active Ingredient Analysis | Assay, identification, structural peak profiling via HPLC / UV. |
| Hazardous Substance Analysis | Heavy metals, pesticide residue, solvent residue validation. |
| Microbe Analysis | Bacterium, Escherichia coli, Yeast & mould, specific microbial tests. |
| Raw Material Control | Pesticide residue, allergen screening, GMO testing, verified origin maps. |
| Laws & Regulations Confirmation | Continuous alignment with pharmacopeial updates across China, the EU, USA, and international territories. |
| Stability Test | Guaranteed shelf life and active ingredient efficacy over time under accelerated climate simulations. |
| Others | pH value, moisture, ash, optical rotation, particle size, bulk/tapped density, etc. |
| Analytical Instrument | Quantity Available | Key Utility Scope |
|---|---|---|
| UHPLC, Agilent 1290 | 2 Units | Ultra-High Pressure separation for rapid quantification of complex marker components. |
| HPLC, Agilent 1260 | 4 Units | High precision active assay analysis and compound profiling. |
| HPLC, Shimadzu LC-20AT | 2 Units | Standard batch release testing and active validation testing. |
| ELSD, Shimadzu 2000ES | 2 Units | Detecting compounds that lack chromophores (e.g., lipids, sugars, saponins). |
| Shimadzu GC-2010 | 1 Unit | Residual solvent profile screening and essential oil evaluation. |
| Shimadzu AA-7000 | 1 Unit | Heavy metal detection (Arsenic, Lead, Cadmium, Mercury). |
From university collaboration laboratories to wild-harvested and GACP agricultural fields.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Addressing core questions regarding Doctor Mito Berberis pharmacology, manufacturing, and supply.
Explore our foundational plant extract systems developed for target applications.
