Explore our elite portfolio of high-purity botanical raw materials utilized globally for cholesterol reduction, lipolysis enhancement, and metabolic optimization.
Understanding the cellular pathways through which plant-derived bioactives modulate lipid profiles and cardiovascular risk factors.
Natural compounds such as Berberine act as potent AMPK (Adenosine Monophosphate-Activated Protein Kinase) activators. By turning on this metabolic master-switch, hepatocyte lipid synthesis is down-regulated. Specifically, Berberine has been shown to clinically increase LDL receptor (LDLR) expression on the liver surface through an extracellular signal-regulated kinase (ERK)-dependent pathway, stabilizing LDLR mRNA. This mechanism works orthogonally to statins, which block HMG-CoA reductase, providing a synergistic botanical mechanism to sweep circulating low-density lipoprotein cholesterol (LDL-C) from the bloodstream.
High circulating levels of cholesterol pose the greatest risk when subjected to reactive oxygen species (ROS), yielding oxidized LDL (oxLDL) which initiates plaque formation. High-polyphenol botanical extracts, including Green Tea Extract (EGCG), Resveratrol, and Grape Seed Extract (Oligomeric Proanthocyanidins), function as rapid radical scavengers. They mitigate lipid peroxidation within the bloodstream, protecting the vascular endothelial lining, suppressing foam cell development, and sustaining healthy nitric oxide (NO) generation for optimal arterial elasticity.
In the modern nutraceutical landscape, international brands and pharmaceutical buyers demand more than simple commodity sourcing. Modern procurement models require uncompromising raw material traceability, standardized active compound percentages, and verified safety margins. To meet these requirements, manufacturers must ensure complete chemical profiling of raw materials, ensuring that every cargo contains specific, standardized amounts of active compounds (such as icariin in Epimedium or specific flavonoids in Ginkgo) with minimal trace impurities. Sourcing from verified manufacturing entities guarantees security in supply volume and regulatory stability.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Merging heavy industrial extraction capacity with state-of-the-art automation and strict EU-GMP validation parameters.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The factory has successfully passed the official China GMP certification.
EU-GMP and CEP certification secured for Ginkgo Biloba Extract.
All extraction lines adopt modern, automated control setups.
We own and operate the most advanced extraction systems in mainland China.
Annual processing capability of 30,000 tons of Chinese medicine & plant raw materials.
Includes 3 annular dynamic countercurrent (10t/15t) & 2 multi-functional lines.
Only acetone Ginkgo extraction line in China matching strict EU GMP standards.
Six specialized 20-ton fermentation tanks for advanced enzyme-modified botanical output.
A visually audited view of our real GMP extraction environments and analytical facilities.
United New Life and UniCare have established a leading and complete quality control system, and strictly control the high quality of products in accordance with the quality system.
With advanced testing instruments, strict control of product quality, to provide every customer with high quality products. Detectable items are: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Our key analytical instruments include: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, two HPLC Shimadzu LC-20AT high performance liquid chromatographs, two HPLC Dionex UltiMate 3000, two Shimadzu evaporative light scattering detectors 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
| Instrument Model / Type | Quantity | Primary Application Area |
|---|---|---|
| UHPLC, Agilent 1290 | 2 Units | High-throughput quantitative analysis of complex botanicals |
| HPLC, Agilent 1260 | 4 Units | Standardized biomarker concentration testing & validation |
| HPLC, Shimadzu LC-20AT | 2 Units | Routine purity, validation, and active assay monitoring |
| HPLC, Dionex UltiMate 3000 | 2 Units | Gradient elution profiling and qualitative finger-printing |
| ELSD, Shimadzu 2000ES | 2 Units | Detection of compounds lacking strong chromophores (e.g., lipids/sugars) |
| Shimadzu GC-2010 | 1 Unit | Volatile organic compound limits & organic solvent residue analysis |
| Shimadzu AA-7000 | 1 Unit | Heavy metal detection (Lead, Cadmium, Arsenic, Mercury) |
| QC Parameters | Analytical Scope & Target Thresholds |
|---|---|
| Active Ingredient Analysis | Assay testing, raw material botanical identification, qualitative TLC mapping. |
| Hazardous Substance Analysis | Heavy metal profiles, multi-residue pesticide screening, residual extraction solvents (GC). |
| Microbe Analysis | Total Aerobic Microbial Count (TAMC), Yeast & Mold (TYMC), pathogens including E. Coli and Salmonella. |
| Raw Material Control | Allergy origin validation, GMO checking, geographical origin tracing (GACP). |
| Laws & Regulations Confirmation | Rigorous compliance mapping against GB (China), USP (USA), and EP (Europe) regulations. |
| Stability Test | Long-term and accelerated environmental chambers to guarantee shelf life integrity. |
| Physical Characteristics | pH values, bulk/tapped density, particle size distribution (mesh), moisture contents, and ash residues. |
Combining deep academic collaboration with fully traceable GACP planting fields to secure pure inputs.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through traditional processes and drive industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP (Good Agricultural and Collection Practices) management model.
Why global pharmaceutical and dietary brand giants source their botanical agents through UniCare.
Our planting bases are located within their optimal ecological zones in China. For instance, Epimedium and Ginkgo Rosea bases leverage geographical soil minerals and natural rain patterns, minimizing fertilizer dependency and yielding higher concentrations of key target compounds.
With access to municipal energy infrastructure, our multi-functional lines run continuously without power breaks. Processing 30,000 tons of botanical input annually ensures that global purchase orders are fulfilled regardless of scale, shielding buyers from seasonal market spikes.
We cooperate with advanced plant seedling research companies to develop high-content cultivars. Through hybridization and genetic optimization, we obtain crops that generate higher concentrations of active target chemicals, driving down production and raw material costs.
Navigating the complex landscape of international food and drug safety requires rigorous compliance mechanisms. UniCare handles structural documentation challenges, ensuring seamless integration into foreign domestic markets.
Our high-purity cholesterol-reducing extracts are adapted to multiple industrial application fields:
The cholesterol reduction and metabolic wellness landscape is undergoing major shifts.
Consumers actively reject synthetic chemicals and toxic industrial solvents. The demand for water-only, ethanol-only, or supercritical CO2 extraction methods has risen dramatically. Sourcing clean-label raw materials is crucial for maintaining brand trust.
Combining specific plant alkaloids with enzymatic systems enhances bioavailability. Formulators increasingly combine compound carriers like Berberine with lipids or cyclodextrins to bypass standard absorption bottlenecks in the gut.
Global supply networks require verifiable ESG commitments. Cultivation must respect biodiversity and protect soil health, ensuring long-term access to critical plant species like Epimedium and Ginkgo.
Answering the primary operational questions raised by procurement managers and R&D scientists.
Expanding formulation options with high-potency, standardized natural compounds.
