Explore our core product lines manufactured to global GMP standards.
L-Ergothioneine (EGT) is rapidly establishing itself as the crown jewel of active ingredients in the pharmaceutical, nutraceutical, and premium cosmetic sectors. Unlike standard antioxidants like Vitamin C or CoQ10, EGT utilizes a highly specific cellular transporter mechanism—OCTN1—which allows it to cross cell membranes directly and accumulate inside mitochondria and cell nuclei. This subcellular targeting prevents oxidative DNA damage and maintains ATP production under extreme stress conditions.
As leading exporters, we have seen a paradigm shift in how global brands formulate. Buyers are no longer just asking for standard botanical ingredients; they demand highly biosynthesized actives with proven efficacy, clean labels, and absolute purity. L-Ergothioneine powder is the response to this demand.
Understanding the technical differentiation is critical to sourcing high-value active ingredients.
Historically, Ergothioneine was extracted from rare mushrooms or synthesized chemically. Extraction yields were extremely low, making the product prohibitively expensive. On the other hand, chemical synthesis poses risks of D-isomer contamination, which has no biological activity and presents safety concerns. Today, our partners employ advanced metabolic engineering of yeast (Saccharomyces cerevisiae) or E. coli. By optimizing the pathway using non-pathogenic organisms, we produce 100% pure L-Ergothioneine without heavy metal catalysts or toxic organic solvents.
In North America and Europe, the demand for L-Ergothioneine is driven heavily by the anti-aging cosmetic market (skin repair, UV-induced inflammation shield) and brain-health dietary supplements. In the Asia-Pacific region, functional foods and cosmetics are the primary drivers. Companies looking for high-quality, continuous supplies need to align with factories that not only provide documentation but can demonstrate scalable production with deep R&D backing.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplements, food, cosmetics, and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EU-GMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Four core pillars guiding our research, development, and customer support.
Unlocking potential in botanical extracts using modern molecular sciences.
Constantly optimizing fermentation pathways and raw material extraction yields.
Equipping our facilities with top-tier extraction and purification lines.
Supporting sustainable farming communities and dynamic workforce development.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
China GMP Certification: The manufacturing facility has passed strict domestic GMP compliance protocols.
EU-GMP & CEP Certification: Globally recognized certifications for critical active lines like Ginkgo Biloba Extract.
Automated Control Systems: Intelligent digital integration for absolute batch consistency.
Advanced Extraction Hardware: State-of-the-art systems featuring cutting-edge purification engineering.
30,000 Tons Annual Capacity: Processing massive volumes of Chinese medicine and raw materials yearly.
Six Dynamic Extraction Lines: 3 annular dynamic countercurrent (10t & 15t), 2 multi-functional lines (32 tanks), 1 round dynamic line.
Unique Acetone Process: The only plant in China that conforms to EU-GMP standards for this specialized process.
Fermentation Infrastructure: Six 20-ton capacity fermentation tanks dedicated to enzyme-modified products and biosynthetic L-Ergothioneine.
Strict analytical validation guarantees the biological activity and purity of every batch.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. Equipped with advanced testing instruments, we perform strict checks on active concentrations, residual impurities, and potential hazards.
| Quality Control Segment | Specific Parameters & Methodologies |
|---|---|
| Active Ingredient Analysis | Assay testing, molecular identification, isomer purity (L-isomer vs. D-isomer validation) |
| Hazardous Substance Analysis | Heavy metals profiling, pesticide residues, organic solvent residues monitoring |
| Microbe Analysis | Total viable count, Escherichia coli, yeast & mold, specific pathogenic microbial tests |
| Raw Material Control | Pesticide residue pre-screening, allergen origin analysis, GMO testing, raw material geographic tracking |
| Laws & Regulations Confirmation | Ongoing investigation and regulatory alignment with FDA, EFSA, NMPA standards |
| Stability Test | ICH guidelines based shelf life verification (temperature, humidity, light chamber testing) |
| Physical Parameters | pH value, moisture, ash, optical rotation, particle size, bulk density, tap density |
Our analytical labs utilize instruments from Agilent, Shimadzu, and Dionex to ensure structural confirmation and exact quantitative measurements.
| UHPLC, Agilent 1290 (×2) | Ultra-High Performance Liquid Chromatography for rapid assay determinations |
| HPLC, Agilent (×4) & Shimadzu LC-20AT (×2) | Standard high-performance assays and raw material validation |
| Dionex CU3000 (×2) & ELSD Shimadzu 2000ES (×2) | Evaporative light scattering detectors for sugars, lipids, and compounds without chromophores |
| Shimadzu GC-2010 (×1) | Gas chromatography for residual solvents and volatile impurities |
| Shimadzu AA-7000 Atomic Absorption (×1) | ICP-MS alternative for precision testing of toxic heavy metals |
At UniCare, we invest 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
To further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP (Good Agricultural and Collection Practices) management model.
In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
A roadmap for global sourcing, customs clearance, and active registration.
In Europe, Ergothioneine is approved for use in cosmetic formulas (CosIng registry). In the USA, it is GRAS (Generally Recognized as Safe) for specific food uses and widely integrated in cosmetics under FDA guidelines. In China, it is registered in the Inventory of Existing Cosmetic Ingredients (IECIC). We provide full dossier packets, MSDS, COA, and structural verification documentation to support raw material registration.
Because EGT is a high-value active powder, we package it in double-layered pharmaceutical-grade PE bags inside sealed fiber drums, with option for vacuum packaging. Standard packaging ranges from 1kg/aluminum foil bag to 25kg/drum. We offer air freight shipping with temperature-controlled logistics to guarantee maximum product integrity upon arrival.
Critical information for corporate procurement officers and formulation scientists.
We supply L-Ergothioneine powder with a minimum purity of 99.0%, with typical production batches reaching 99.5%+ assay validated by UHPLC. We ensure that 100% of the active is the biologically active L-isomer, with no detection of the inactive D-isomer.
We utilize advanced submerged microbial fermentation. This method ensures that the product is non-GMO, clean-label, vegan-friendly, and completely free from the toxic chemical catalysts and solvents associated with traditional chemical synthesis.
Yes. Every batch undergoes extensive internal testing at our CNAS-qualified laboratory. Additionally, we work with accredited third-party laboratories (such as SGS, Eurofins, or Intertek) to provide independent validation of purity, heavy metals, pesticide residues, and microbial counts upon customer request.
We provide a comprehensive documentation package including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheets (TDS), Flow Charts, GMO statements, Allergen statements, and BSE/TSE-free certification.
Yes. Our dynamic production lines allow us to optimize parameters such as particle size (mesh sizes for tablets, capsules, or liquid suspensions) and bulk density to match the exact requirements of your formulation equipment.
We perform ongoing real-time and accelerated stability testing in strict compliance with ICH guidelines. L-Ergothioneine is structurally very stable; however, we package it in light-resistant, moisture-barrier packaging to ensure a shelf-life of 24 months when stored under cool, dry conditions.
Explore our plant extract portfolio with proven efficacy and robust supply chains.
