High-purity botanical extractions and pharmaceutical-grade chemical compounds tailored for global healthcare and industrial applications.
Goldenseal (Hydrastis canadensis) is a highly valued North American perennial herb containing potent isoquinoline alkaloids, primarily hydrastine, berberine, and canadine. In the global toxicology and drug testing sector, Goldenseal plays a dual role. Historically known for the false assumption that ingestion could mask illicit substance usage (such as THC) in urine screens, it has pushed the forensic and workplace testing industry to implement specialized assays. These assays verify sample integrity by tracking specific metabolites of Goldenseal to confirm sample adulteration or natural botanical interference.
As a leading supplier and exporter, UniCare offers premium, ultra-pure, standardized Goldenseal extract intermediates. These are engineered specifically for diagnostic kit manufacturers, analytical laboratories, and research institutions globally. Our specialized extraction pipelines isolate high-purity alkaloids to serve as reference materials and positive controls in diagnostic assay verification panels.
Without standardized hydrastine and berberine profiles, diagnostic kits cannot correctly distinguish between deliberate specimen dilution, natural dietary intake, and intentional masking attempts. UniCare's manufacturing standards guarantee consistent alkaloid fingerprints for accurate validation.
From clinical laboratories to forensic testing facilities, discover where our standardized products are applied.
Corporate and industrial workplace environments utilize specimen screening to verify sample integrity, using our standards to establish baselines that rule out masking agents.
Legal and law-enforcement diagnostic labs rely on high-precision LC-MS/MS verification. They require precise levels of hydrastine and canadine to validate adulterated urine specimens.
Global diagnostic strip developers integrate our high-purity active markers into strip validation assays to check for the presence of natural herbal adulterants.
Our path forward in extraction technology, bio-molecular assay standardization, and synthesis development.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
UniCare leverages China's industrial infrastructure to offer high quality, reliable supply, and competitive pricing.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
This massive scale guarantees stability in supplying raw materials for diagnostics and drug test components, safeguarding our global partners against supply shocks, crop failures, or regulatory shifts.
Facility complies with China GMP guidelines.
Ginkgo Biloba Extract certified for EU quality standards.
Fully automated lines guarantee batch-to-batch consistency.
Equipped with high-performance countercurrent extraction lines.
High-volume processing capacity ensures continuous supply.
Three annular dynamic countercurrent (10t/15t) & two multi-functional lines.
The only acetone line in China meeting EU GMP regulations.
Six 20-ton capacity tanks for enzyme-modified products.
Strict adherence to national and international standards using state-of-the-art laboratory testing equipment.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products. Detectable items are: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Important testing instruments are: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, There are two HPLC Shimadzu LC-20AT high performance liquid chromatograph, two HPLC Diane CU3000, two Shimadzu evaporative light scattering detector 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
| Quality Control Classification | Specific Testing Scope & Analytical Items |
|---|---|
| Active Ingredient Analysis | Assay, compound identification, alkaloid ratio verification (hydrastine/berberine) |
| Hazardous Substance Analysis | Heavy metals (ICP-MS), pesticide residue (GC-MS-MS), residual solvent trace analysis (GC) |
| Microbe Analysis | Total aerobic microbial count (TAMC), Escherichia coli, Yeast & mould count, specific pathogen assays |
| Raw Material Control | Adulterant validation, GACP verification, non-GMO compliance, geographical origin tracing |
| Laws & Regulations Confirmation | Compliance check against US FDA, EU Pharmacopoeia, Chinese Pharmacopoeia, and international drug regulations |
| Stability & Shelf Life | Accelerated and long-term stability profiling to establish precise shelf-life claims |
| Physical/Chemical Properties | pH value, moisture, ash content, optical rotation, particle size distribution, bulk density |
| UHPLC, Agilent 1290 (×2) | HPLC, Agilent (×4) | HPLC, Shimadzu LC-20AT (×2) |
| ELSD, Shimadzu 2000ES (×2) | Shimadzu GC-2010 (×1) | Shimadzu AA-700 (×1) |
How we balance advanced biotechnology with sustainable agricultural partnerships to secure high-quality botanical raw materials.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling R&D companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
A look inside our advanced extraction facility, high-precision storage, and automated packaging departments.
Technical guidance regarding alkaloid profiles, assay interference, detection thresholds, and supply chain logistics.
Toxicology and forensic laboratories screen specimens for hydrastine and canadine using gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS). While berberine is a major alkaloid of Goldenseal, it is also present in other botanical species like Barberry and Goldthread. Therefore, hydrastine and canadine serve as the definitive biomarkers for identifying *Hydrastis canadensis* ingestion.
No. Scientific studies show that Goldenseal does not mask illicit drugs or their metabolites in urine toxicology screens. The myth stems from historical anecdotal claims. However, excessive consumption of Goldenseal root extracts alongside large volumes of water can cause sample dilution. Today's labs utilize specific gravity, creatinine checks, and direct biomarker assays to identify diluted samples and detect masking agents.
We utilize high-resolution UHPLC (Agilent 1290) and GC-MS-MS screening systems to verify the alkaloid profile of each batch. Our extraction processes are strictly controlled under GMP conditions, verifying the hydrastine-to-berberine ratio is consistent and free from heavy metals, pesticides, or organic solvent residues.
We offer custom standardization profiles. Our standard catalog includes Goldenseal extracts standardized to 5% Hydrastine, 10% Berberine, and purified single-alkaloid compounds (>98% purity by HPLC) for analytical calibration, testing validation, and reagent formulation.
Yes. Our raw material procurement system reaches every piece of planting land for batch traceability. Important planting partners establish bases (including Ginkgo, Epimedium, Phellodendron, and Olive bases) managed under the GACP model to guarantee high quality and a sustainable, stable raw material supply.
As an experienced global exporter, we provide a complete documentation package with every shipment, including Certificates of Analysis (COA), MSDS, Allergen statements, and GMO-free declarations. We keep abreast of regulations in the US, Europe, and Asia to help ensure smooth customs clearance and import compliance.
Premium-grade standard extracts produced in our automated Chinese GMP facilities for diverse industrial needs.
