Explore our high-performance ingredients, manufactured in compliance with international quality standards for pharmaceutical, health, and dietary supplements.
UniCare stands at the forefront of the global plant extraction industry as a premium developer and supplier of natural active ingredients. Our high-purity phytochemical compounds, notably our flagship product line Natural Fisetin Extract, serve the demanding requirements of the global dietary supplement, functional food, pharmaceutical, and high-end cosmetic sectors.
We believe in building sustained partnerships by ensuring strict quality control, optimizing industrial processes, and executing reliable cross-border logistics. To secure consistent production capacity, UniCare maintains profound strategic alliances with China's leading manufacturing units, possessing complete quality assurance credentials like GMP, EU-GMP, CEP, ISO9001, ISO22000, and HACCP.
Every facility is backed by modern analytical instrumentation to verify purity levels, stability profiles, and contaminant absence, ensuring each batch delivers exact, high-potency active molecules.
Driving scientific validation and technological advancement in botanical raw materials to fulfill the global demand for health and longevity.
We strive to identify active botanical fractions and convert their inherent bioactivity into high-value raw compounds for formulation development.
Constantly improving yields, solvent recovery techniques, and chemical purification methodologies to assure competitive cost advantages.
Employing automated dynamic countercurrent extractors and modern HPLC-monitored crystallization to achieve ultra-high compound purity.
Supporting local agricultural partners through GACP crop management, protecting wild resources, and minimizing eco-footprints.
Uncovering the metabolic path, purity standards, and cellular aging mechanisms of botanical Fisetin.
Natural Fisetin (3,7,3',4'-tetrahydroxyflavone) is a naturally occurring dietary flavonol primarily extracted from the wood of Cotinus coggygria (commonly known as Smoke Tree). Over the last decade, cellular medicine and gerontology researchers have classified Fisetin as one of the most potent natural senolytics. Senolytics are substances that selectively target and eliminate senescent cells—colloquially called "zombie cells"—which accumulate with age and secrete pro-inflammatory cytokines, causing tissue degeneration.
Our extraction methodologies prioritize physical isolation and crystallizing steps that preserve the original structure of the molecule. Standardized Fisetin extracts from UniCare reach a verified purity of ≥98% by HPLC. Our process selectively extracts active flavonols without introducing chemical impurities common in synthetic processes, ensuring natural synergy when combined with other compounds such as Quercetin or Resveratrol.
Each manufacturing run undergoes extensive chromatography mapping to confirm that no peaks from heavy structural analogs are present, guaranteeing pure, high-potency Fisetin.
Assay Specification: ≥98% Pure Active Fisetin (HPLC)Our extraction infrastructures integrate automated technologies, eco-friendly processing, and vast annual capacities.
Our collaborative production hubs are fully China-GMP certified, guaranteeing that all raw material reception, handling, and chemical isolation follow strict GMP rules.
We boast the only acetone process Ginkgo Biloba Extract production line in China that meets the EU GMP and CEP standards, confirming our capacity to handle specialized active ingredients.
All key lines utilize smart DCS systems, managing temperature, flow rate, pressure, and crystallization times automatically to minimize batch deviations.
Our facilities process over 30,000 tons of Chinese medicinal herbs annually, backed by high-capacity material warehouses and constant raw herb supply lines.
Equipped with 6 dynamic countercurrent pipelines (10-ton & 15-ton configurations) and multi-functional extraction tanks to process varied densities and plant parts.
We manage six 20-ton bio-fermentation tanks for enzyme-modified compounds, bridging classic botanical extraction with modern biotechnology.
The China Supply Chain Advantage: As a leading Fisetin source exporter, UniCare leverages China's industrial chemical extraction cluster. This allows us to source raw *Cotinus coggygria* branches efficiently, benefit from highly optimized local logistics, and run large-scale crystallization plants. These factors combine to offer international supplement brands competitive price structures, stable supply chains, and reliable year-round delivery.
Ensuring complete product traceability, starting from GACP-aligned farming and crop selection.
UniCare invests 10% of our annual net profit back into scientific research and development. To explore new biological pathways, we collaborate closely with the Beijing University of Chemical Technology. This joint effort focuses on bio-enzymatic conversion techniques and structural identification, helping us turn new health molecules into large-scale commercial ingredients.
To control heavy metals, agricultural pesticide residues, and active chemical profiles right from the source, UniCare works directly with local growers. We run dedicated planting bases for Ginkgo, Epimedium, Phellodendron, and Olive Leaf. Key portions of these crops are managed under strict GACP rules. Furthermore, we develop improved crop strains via hybrid and non-GMO optimization, increasing active compound yields while lowering farming costs.
Operating a qualified central laboratory using advanced analytical instruments to verify the physical and chemical safety of every batch.
Our quality system is designed to comply with international regulations, including the US FDA, European Food Safety Authority (EFSA), and Japan's MHLW guidelines. Our central laboratory has a testing footprint that verifies physical properties, molecular content, and contaminant profiles. Key monitored parameters include active marker content, volatile residual solvents (via Gas Chromatography), heavy metals (via ICP-MS), multi-class pesticide residues, and microbiological purity.
| Quality Parameter Checked | Analytical Methodology / Equipment Employed |
|---|---|
| Active Compound Assay | HPLC & UV Identification against certified USP reference standards |
| Pesticide Residual Screen | GC-MS-MS organochlorine and organophosphorus tracking |
| Organic Solvent Residuals | Headspace Gas Chromatography (GC) for ethanol/acetone limits |
| Heavy Metals (As, Pb, Cd, Hg) | ICP-MS (Inductively Coupled Plasma Mass Spectrometry) detection |
| Physical Properties | Sieve mesh size, tap density, moisture content, and ash content |
| Microbiological Parameters | Total plate count, yeast & mold, E. coli, Salmonella identification |
| Regulatory & Stability Verification | Real-time and accelerated stability studies in environmental chambers |
Our analytical capacity is supported by premium instrumentation, including:
| Instrument Class | Manufacturer & Model Details | Quantity |
|---|---|---|
| Ultra-High Performance Liquid Chromatograph (UHPLC) | Agilent 1290 Series | 2 Units |
| High-Performance Liquid Chromatograph (HPLC) | Agilent 1260 / Shimadzu LC-20AT / Dionex U3000 | 8 Units |
| Evaporative Light Scattering Detector (ELSD) | Shimadzu 2000ES | 2 Units |
| Gas Chromatograph (GC) | Shimadzu GC-2010 | 1 Unit |
| Atomic Absorption Spectrophotometer (AAS) | Shimadzu AA-7000 | 1 Unit |
Helping global supplement brands meet local compliance and streamline cross-border supply chains.
We supply complete technical dossiers, including allergen files, TSE/BSE-free statements, Non-GMO statements, and detailed DMF files to help you secure fast local product approvals.
We closely monitor regulatory updates across major markets like the US FDA (NDI, GRAS), EU Novel Food catalogs, and EFSA standards, ensuring our Fisetin remains compliant for import.
Through our global logistics network, we offer DDP shipping option, clear customs, and partner with regional storage hubs to ensure prompt, secure deliveries to your manufacturing site.
The anti-aging and health market is evolving. See how Fisetin is formulated across diverse product categories.
The global senolytic supplement market is growing rapidly, driven by interest in healthy aging, cellular rejuvenation, and preventive healthcare. Consumers are looking for plant-based ingredients backed by scientific research, moving away from synthetic alternatives. Natural Fisetin is becoming a key ingredient in next-generation longevity formulations due to its high bioactivity and clear clinical data.
Furthermore, as research validates the synergistic effects of combining Fisetin with other flavonoids (like Quercetin and Resveratrol), multi-ingredient cellular health formulas are capturing a larger share of the wellness market.
Standardized botanical extracts and active complexes developed to support global brand formulations.
Direct technical explanations from our quality assurance team regarding natural Fisetin sourcing, purity, and manufacturing standards.
