Quercetin (3,3',4',5,7-pentahydroxyflavone) stands as one of the most clinically-researched bioflavonoids globally. Primarily derived from botanical sources such as Sophora japonica L. (Japanese pagodatree), onion skins, and apples, it is highly demanded by the global nutraceutical, cosmetic, and pharmaceutical industries due to its potent antioxidant, anti-inflammatory, and senolytic health benefits.
As consumer awareness of immune resilience and longevity stacks grows, manufacturers are moving towards ultra-pure, standardized, and clean-label dietary ingredients. Global market volume is expected to rise sharply, forcing procurers to seek premium global factories capable of scale, regulatory compliance, and biological performance.
To qualify as a top-tier supplier, factories must demonstrate batch-to-batch stability, control residual solvents under strict pharmacopoeial limits (USP/EP), maintain clean drying parameters, and achieve highly standardized mesh sizes for optimal formulation flowability.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
China is the global powerhouse for herbal extractions, supplying over 80% of the world's Quercetin. This concentration offers distinct upstream and downstream advantages:
Our collaborative farming agreements and extensive raw material silos hold sufficient dry Sophora buds to run extraction lines round-the-clock, insulating customers from seasonal crop failures or sudden market surges.
Why Choose Us?
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The factory strictly conforms to China GMP manufacturing and sanitary regulations.
Ginkgo Biloba Extract lines are certified under European regulatory parameters.
DCS control systems regulate extraction, temperature, and solvent recovery.
Equipped with high-performance glass-lined reactors and stainless steel extractors.
Scalable processing of botanical raw materials to ensure stable batch volumes.
Includes three dynamic countercurrent lines and two multi-functional systems.
The only EU GMP compliant acetone process Ginkgo line in China.
Six 20-ton fermentation tanks for biocatalyzed and enzyme-modified products.
To address Quercetin's natural limitations in solubility and absorption, our R&D team works closely with leading academic centers to pioneer next-generation delivery platforms.
Traditional Quercetin Dihydrate/Anhydrous at 95%-98% purity, ideal for capsule formulas with classic oil-suspension binders.
Particle-size engineering (down to 80-120 mesh) to increase dissolution surface area and formulation compatibility.
Complexing Quercetin with food-grade lecithin to enhance cellular membrane transport and increase bioavailability up to 10-fold.
Developing water-soluble Isoquercitrin (EMIQ) via biotechnology for functional beverage and quick-melt sachet lines.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products.
Detectable Items: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Important Testing Instruments: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, two HPLC Shimadzu LC-20AT high performance liquid chromatographs, two HPLC Dionex UltiMate 3000, two Shimadzu evaporative light scattering detectors 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
| Quality Control Section | Specific Quality Testing Items & Validation Parameters |
|---|---|
| Active Ingredient Analysis | Assay, chemical profile identification, HPLC-DAD fingerprinting |
| Hazardous Substance Analysis | Heavy metals (Pb, As, Hg, Cd), organochlorine pesticide residues, residual solvents (ethanol, methanol) |
| Microbe Analysis | Total viable aerobic count, Escherichia coli, Yeast & mold, Salmonella, specific pathogens |
| Raw Material Control | GACP tracing, botanical identity verification, allergen screening, GMO testing |
| Laws & Regulations Confirmation | Compliance reviews according to FDA GRAS, EFSA Novel Food, and Chinese Pharmacopoeia |
| Stability Test | Accelerated and long-term shelf-life study validation under variable humidity & temperature conditions |
| Physical & Chemical Parameters | pH value, moisture, ash, optical rotation, bulk/tapped density, particle size mesh distribution |
| Analytical Equipment | Laboratory Quantity & Verification Standard |
|---|---|
| UHPLC, Agilent 1290 | 2 units (Used for high-resolution rapid analysis of multi-component assays) |
| HPLC, Agilent 1260 / Shimadzu LC-20AT / Dionex | 8 systems combined (Routine high-volume batch release assay verification) |
| ELSD, Shimadzu 2000ES | 2 units (Specifically configured for compounds lacking strong UV chromophores) |
| Shimadzu GC-2010 | 1 system (Solvent residue recovery validation and monitoring) |
| Shimadzu AA-7000 / ICP-MS | 1 atomic absorption system (Trace element and heavy metal screening) |
Research & Development Focus
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
Traceable Sourcing & Cultivation
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Widely used in dietary supplements, daily immune stacks, and energy capsules. Requires complete DSHEA compliance, allergen-free labeling, and FSMA-compliant supply chain records.
Popular in functional nutrition and healthy aging formulations. Sourcing must comply with EFSA Novel Food regulations, strict PAH limits, and zero Ethylene Oxide (EtO) cross-contamination.
Integrated into traditional herbal formulas, hangover cure beverages, and natural cosmetics. Products require high water solubility, stable pH tolerance, and clean-label trace tracking.
