Highly standardized herbal actives manufactured to satisfy global regulatory frameworks.
Understanding the therapeutic intersections of Berberine and Resveratrol on a global scale.
In the global nutraceutical market, formulation design has undergone a paradigm shift from single-molecule supplementation to target-oriented compounding. Berberine and Resveratrol represent the pinnacle of this shift. Berberine, historically sourced from Coptis chinensis or Berberis aristata, functions primarily as a potent cellular sensor. It triggers the activation of AMP-activated protein kinase (AMPK), often termed the metabolic master switch. This enzymatic pathway shifts cells from nutrient storage to utilization, normalizing blood glucose parameters and enhancing insulin sensitivity.
Concurrently, Resveratrol operates via complementary pathways. As a natural polyphenol typically sourced from Polygonum cuspidatum or grape skins, it targets the Sirtuin-1 (SIRT1) gene sequence. SIRT1 mimics calorie restriction benefits, promoting mitochondrial biogenesis and protecting cells against severe oxidative stress. By leveraging this combined mechanism, industrial-scale formulary brands are creating high-impact metabolic longevity blends. As a leading exporter, UniCare offers highly pure compounds optimized for bioavailability, matching the exact regulatory specifications of diverse global markets.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Connecting ancient botanical wisdom with leading-edge engineering processes.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world. We bridge the gap between complex Chinese botanical supply chains and international brands requiring flawless regulatory documentation, continuous supply, and high-purity guarantees.
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Deploying scale, advanced tech, and intelligence to optimize extraction.
Why Choose Us?
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
GMP Certified Facility: Passing rigorous domestic and global audits.
EUGMP and CEP Certified: Complete regulatory validation for European target markets.
Automated Control: Full PLC system monitoring temperature, flow, and vacuum pressures.
Top-Tier Hardware: Built with high-grade anti-corrosive stainless steel systems.
30,000 Tons Output: Securing stable year-round inventories for multinational brands.
Diverse Extractions: 3 annular dynamic countercurrent lines (10T & 15T) and 32 multi-functional extraction tanks.
Acetone Process Excellence: Only acetone Ginkgo process in China to pass EU GMP guidelines.
Biotech & Fermentation: Six 20-ton fermentation tanks for novel bio-transformed molecules.
Visual verification of our operations, standard operating practices, and heavy machinery layout.
Providing ultimate transparency, reliability, and chemical consistency through leading testing protocols.
United New Life (UniCare) has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products. Detectable items are: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Our analytical team operates out of a centralized lab setting. Important testing instruments are: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, there are two HPLC Shimadzu LC-20AT high performance liquid chromatograph, two HPLC Diane CU3000, two Shimadzu evaporative light scattering detector 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
| Quality Control Parameter | Testing Methodology / Targeted Indicators |
|---|---|
| Active Ingredient Analysis | Assay, Identification (HPLC-DAD, UV-Vis, TLC confirmation) |
| Hazardous Substance Analysis | Heavy metals (ICP-MS), pesticide residue (GC-MS/MS), residual solvents (GC-Headspace) |
| Microbe Analysis | Total plate count, Escherichia coli, Yeast & mould, Salmonella, and specific pathogens |
| Raw Material Control | Allergen profiles, GMO identification, geographical authentication, heavy metal pre-checks |
| Laws & Regulations Confirmation | Cross-border verification of regulatory updates in China, FDA (US), EFSA (EU), and APAC agencies |
| Stability Test | Long-term and accelerated stability profiles (temperature/relative humidity chambers) |
| Others | pH value, moisture, ash, optical rotation, particle size, bulk/tapped density, etc. |
| UHPLC, Agilent 1290 (×2) | HPLC, Agilent 1260 (×4) | HPLC, Shimadzu LC-20AT (×2) |
| ELSD, Shimadzu 2000ES (×2) | Shimadzu GC-2010 (×1) | Shimadzu AA-7000 (×1) |
Guaranteeing biological authenticity from the soil to the shipping container.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development. UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Advancing botanical extraction via green chemistry, molecular optimization, and biological transformation.
In response to global sustainability trends, UniCare is actively researching new solvent strategies for plant extracts. Our technological roadmap includes replacing standard solvent processes with supercritical CO2 and pressurized liquid extraction systems. For products like Resveratrol, we are targeting high-yield crystallization methods that minimize raw solvent waste, lowering carbon output during processing. Concurrently, for Berberine HCl extraction, we are shifting raw material bases to phellodendron varieties cultivated in GACP zones to maintain consistent alkaloid ratios without stressing wild biomes.
The next phase of UniCare's growth focuses heavily on synthetic biology. By integrating engineered yeast strain platforms, we plan to commercialize bio-resveratrol, which features zero pesticide contamination and reduces production footprints by over 60%. This approach will run parallel to our traditional physical plant extraction techniques to cater to multiple industrial buyers. Whether our customers require certified organic botanical extracts or high-purity biotechnological active substances, UniCare has the pipeline ready to deliver.
We supply products with full traceability reports, including heavy metal indexes tailored to US FDA limits (Lead < 0.5 ppm, Cadmium < 0.5 ppm), and European EP 10.0 residue standards. Our logistical pathways offer complete customs clearance documentation, preventing port delays and assuring zero-contamination handovers to distribution lines in North America, Western Europe, and the Asia-Pacific region.
Providing actionable insights and expert-level answers for QA managers and product developers.
Advanced botanical selections optimized for clinical applications and functional beverages.
