China Berberine Root Extract Supplier & Exporter

Premium Crystalline Dietary Ingredients & Global High-Yield Phytochemical Sourcing Solutions. GMP Certified Extraction Infrastructure for Advanced Nutraceutical Formulations.

About UniCare

UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplements, food, cosmetics, and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.

UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.

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About UniCare Lab Facility

Our Core Philosophy

Discover value

Value Creation

Discover and create the new value of herb using advanced analytical tools and biological assays.

Innovation

Continuous Innovation

Continuous innovation and improvement of extraction processes to maximize yield and purity levels.

Technology

Advanced Technology

Utilizing state-of-the-art technologies to produce the highest quality botanical active products.

Social responsibility

Social Contribution

Supporting sustainable harvesting practices, keeping employees happy, and giving back to the community.

Berberine Root Extract: Industrial & Macro Market Perspectives

Unlocking the full chemical and therapeutic potential of Berberine Hydrochloride (HCl) through scientific research, reliable sourcing, and global regulatory compliance.

1. Macro Industry Solutions

The global demand for high-purity Berberine Root Extract has spiked, driven by clinical validations highlighting its role in metabolic health, insulin sensitivity regulation, cardiovascular support, and AMPK pathway activation. However, formulators face critical challenges such as raw material adulteration, heavy metal accumulation, and variable alkaloid yields.

As a leading Chinese supplier, UniCare provides macro-level solutions by utilizing highly selective chromatography and recrystallization processes. This ensures our Berberine HCl (typically derived from Berberis aristata, Phellodendron amurense, or Coptis chinensis) remains free from synthetic adulterants and complies with rigorous global pharmacopoeias (USP, EP).

2. Global Commercial & Industrial Status

China stands at the center of the global Berberine supply chain, possessing the unique botanical resources and large-scale manufacturing infrastructure needed to make production economically viable. Wild harvest limitations have prompted a major shift toward sustainable, GACP-compliant cultivation of raw materials.

Industrially, Berberine is prepared under tight control to avoid hazardous solvents. Modern buyers require complete documentation (including third-party pesticide profiling and residual solvent testing). UniCare leads this space by integrating full batch traceability from local agricultural fields to finished crystalline powder.

>98%
Purity Grade (HPLC)
30,000T
Annual Processing Capacity
10%
Net Profit Invested in R&D
100%
GACP Traceable Sourcing
Production Hardware Icon

Why Choose UniCare?

UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.

Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.

  • GMP Certification: The factory has passed the China GMP certification.
  • EU-GMP & CEP Standards: The EU-GMP and CEP of Ginkgo Biloba Extract has been certificated.
  • Intelligent Control: All extraction production lines adopt modern, intelligent and automated control systems.
  • Advanced Hardware: Own the most advanced extraction equipment in China.
  • Large Capacity: Annual processing of 30,000 tons of Chinese medicine and plant raw materials.
  • Optimized Extraction Lines: Six production lines: Three annular dynamic countercurrent extraction lines (10 tons & 15 tons); two multi-functional extraction lines (32 extraction tanks with six cubic each); one round dynamic countercurrent extraction line (10 tons).
  • Acetone Process Extraction: Own the only acetone process extraction line for Ginkgo Biloba Extract in China that meets the EU GMP standards.
  • Fermentation Capabilities: Own six fermentation tanks (20 tons capacity for each) for the production of enzyme-modified products.
UniCare Production Facility Overview

Quality Control System & Instrumentation

United New Life / UniCare has established a leading and complete quality control system, strictly maintaining product purity and compliance across all botanical batches.

With advanced testing instruments and strict quality gates, we provide every customer with verified high-quality products. Detectable items include: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, pH, sulfur dioxide residue, routine detection, etc.

Analytical Instrumentation Capacity

Our quality verification processes are supported by an advanced array of scientific analytical equipment:

Instrument Model & Brand Quantity Available Primary Testing Application
UHPLC, Agilent 1290 (Ultra-High Performance Liquid Chromatography) 2 Sets Ultra-precise signature chemical profiling & assay checks
HPLC, Agilent 1260 (High-Performance Liquid Chromatography) 4 Sets Active ingredient quantification & purity mapping
HPLC, Shimadzu LC-20AT 2 Sets Routine identification and standard assays
ELSD, Shimadzu 2000ES (Evaporative Light Scattering Detector) 2 Sets Detection of compounds lacking chromophores (e.g. lipids, sugars)
Shimadzu GC-2010 (Gas Chromatograph) 1 Set Residual solvent and pesticide screening
Shimadzu AA-700 (Atomic Absorption Spectrophotometer) 1 Set Heavy metal detection (Lead, Arsenic, Cadmium, Mercury)

Quality System Controls

Control Parameters Details & Operational Scope
Active Ingredient Analysis Assay testing, identification, chemical footprint analysis
Hazardous Substance Analysis Heavy metal analysis, pesticide residues, residual organic solvents
Microbe Analysis Bacterium plate counts, Escherichia coli, Yeast & mould, specific pathogen testing
Raw Material Control Pesticide residue at the farming stage, allergen checks, GMO statuses, botanical origin validation
Laws & Regulations Confirmation Monitoring regulatory changes in China, US FDA, EU EFSA, and target international markets
Stability Test Establishing and guaranteeing shelf life using real-time and accelerated stability studies
Others pH value, moisture, ash, optical rotation, particle size, bulk density, etc.
Testing Lab Agilent Chromatographs High Performance Liquid Chromatography Unit Gas Chromatograph Setup
Testing and Lab Assays CNAS Qualified Lab Equipment

R&D and Raw Material Planting & Procurement

From seed to active ingredient, we maintain full oversight of our botanical supply chains.

R&D Lab Research

Research & Development Paradigm

UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through traditional processes and disrupt industry development.

UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming new raw materials for pharmaceutical, cosmetic, and natural health products into mass-produced products.

Raw Material Planting Field

GACP Sourcing & Base Partnerships

To control raw materials efficiently and with higher quality, we use a procurement system that traces materials back to each specific plot of land. Raw material storage is run according to our quality management system, where active content, moisture, ash, heavy metals, and pesticide residues are checked before processing.

To ensure consistent quality for key products, UniCare partners with farmers to manage dedicated planting bases, including Ginkgo leaf, Epimedium, Phellodendron (crucial for Berberine), and Olive leaf bases. Some are managed strictly under the GACP model. We also partner with research firms to develop high-yield seedlings through selective hybridization to reduce costs for end-users.

Local Support, Custom Logistics, & Regulatory Compliance

Simplifying your botanical import experience with full documentation and responsive logistical pathways.

Regulatory Documentation

We provide comprehensive regulatory dossiers, including allergen statements, non-GMO declarations, Kosher & Halal certificates, and heavy metal profiles. This facilitates smooth registration with the FDA, EFSA, and other local health authorities.

Custom Particle Sizing

Different delivery systems need custom particle distributions. We offer micronization services, customizing mesh sizes for direct tableting, capsule filling, or drink mixes, ensuring optimal blend uniformity.

Logistics & DDP Services

Through our network of global logistics partners, we offer custom-cleared delivery options (including DDP and CIF) to minimize import administration and simplify your supply chain.

Technical Roadmap & Future Outlook

How UniCare is using new green extraction technologies and automated systems to improve phytomedicine manufacturing.

Green Solvent Development

Our engineering team is testing natural deep eutectic solvents (NADES) to reduce organic waste, lowering carbon footprints while maintaining high alkaloid yields.

Bio-Fermentation & Custom Synthesis

Collaborating with the Beijing University of Chemical Technology, we are researching enzymatic transformations to synthesize rare plant compounds that are difficult to extract in large volumes naturally.

Industry 4.0 Smart Refineries

We are upgrading our extraction lines with real-time NIR (Near-Infrared) sensors. This allows continuous monitoring of alkaloid levels during refining, ensuring high batch-to-batch stability.

Frequently Asked Questions

Technical and commercial answers to help with your sourcing and formulation decisions.

What is the primary botanical source of UniCare's Berberine Root Extract? +
Our Berberine Hydrochloride (HCl) is mainly extracted from high-yield, premium *Phellodendron amurense* bark and *Berberis aristata* roots. Every batch is traced to the harvest region to verify its botanical identity and prevent adulteration.
How do you guarantee the removal of heavy metals and pesticide residues? +
Each batch is screened using Shimadzu AA-700 atomic absorption and ICP-MS systems for heavy metals (Lead, Arsenic, Cadmium, Mercury). Pesticides are tested using GC-MS-MS setups to ensure compliance with strict FDA and European regulations.
Can UniCare supply custom particle sizes for tableting? +
Yes, we offer custom milling and micronization services. We can adjust the particle size (e.g., 80 mesh, 100 mesh, or 200 mesh) to match your manufacturing requirements for capsules, tablets, or instant powders.
What quality management certifications do your partner factories hold? +
Our manufacturing partners maintain complete certifications including GMP, EU-GMP, CEP, ISO9001, ISO22000, and HACCP. Our Ginkgo Biloba extract line, for example, is the only EU-GMP compliant acetone extraction line in China.
What is the standard lead time for bulk international shipments? +
Standard orders are processed and shipped within 7 to 15 days from our central warehouse. Custom specifications or custom packaging configurations may take slightly longer, depending on requirements.