Explore our premium grade active botanical ingredients backed by systematic quality management systems.
Beta-glucans are complex structural polysaccharides found in the cell walls of fungi, yeasts, and cereal grains. Unlike cereal-derived beta-glucans which exhibit (1,3 / 1,4) glycosidic linkages, mushroom-derived beta-glucans possess a complex backbone of (1,3)-β-D-glucan with (1,6)-β-linkages branching outward.
This specific molecular configuration of (1,3/1,6) Beta-Glucans acts as a pathogen-associated molecular pattern (PAMP). It interacts specifically with cellular receptor proteins such as Dectin-1, complement receptor 3 (CR3), and Toll-like receptors (TLRs) located on macrophages, natural killer (NK) cells, and dendritic cells.
By activating these key immune cellular pathways, mushroom beta-glucans modulate immune responses, promote cytokine release, and increase host resilience without over-stimulating the systemic inflammatory response. In pharmaceutical, cosmetic, and nutraceutical applications, the biological efficacy of the compound correlates directly with its triple-helix molecular conformation and concentration of active (1,3/1,6) linkages.
A technical guide for procurement agents selecting standardized active ingredients for consumer product formulations.
| Property | Mushroom Beta-Glucan (Fungal) | Yeast Beta-Glucan (Saccharomyces) | Oat/Barley Beta-Glucan (Cereal) | |
|---|---|---|---|---|
| Glycosidic Linkage | β-(1,3)-backbone with β-(1,6)-branches | β-(1,3)-backbone with β-(1,6)-branches | Mixed β-(1,3) and β-(1,4) linear chain | |
| Primary Bioactivity | Deep cellular immune support, anti-fatigue, adaptogenic support | Innate immune response, gut microbiome prebiotic | Cardiovascular health, blood glucose control, dietary fiber | Active biological pathways |
| Solubility Profile | Adjustable (Formulations available in fully water-soluble and suspension grades) | Generally insoluble in water | Viscous, soluble fiber structure | |
| Extraction Method | Multi-stage hot water extraction & membrane filtration | Acid/alkali hydrolysis of yeast cell wall | Mechanical milling and chemical separation | |
| Typical Purity Range | 30% to 80% (Megazyme enzymatic analysis) | 70% to 85% purity | 20% to 50% purity |
How our advanced industrial manufacturing facility in China ensures reliable bulk supply and cost stability.
The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Our extraction setups are engineered for high-throughput separation of high-purity mushroom polysaccharides.
With six advanced multi-functional extraction lines, our factory possesses the capacity to process 30,000 tons of botanical and fungal raw materials annually. This scale guarantees supply security during high-demand quarters.
We work closely with mushroom growers and maintain agricultural planting bases. Our sourcing extends to the point of origin, allowing batch-to-batch traceability for heavy metals, pesticides, and microbial load.
Many generic suppliers rely on non-specific polysaccharide analysis, such as the Phenol-Sulfuric Acid method. However, this method cannot distinguish between target beta-glucans and inactive starch, dextrin, or other alpha-glucans, often leading to inflated purity readings.
UniCare utilizes the industry-standard Megazyme enzymatic method (AOAC 2020.12 or similar standard protocols) to isolate and measure alpha-glucans and total beta-glucans separately. This ensures you receive a precise measurement of the active compound.
Our analytical lab features advanced instrumentation including UHPLC (Agilent 1290), HPLC systems, GC-MS, and ICP-MS for heavy metal quantification down to parts-per-billion (ppb).
Engineered raw materials customized to meet your product development requirements.
We supply fine-mesh powders with enhanced solubility, designed for seamless dispersion in hot or cold functional drinks, liquid shots, and cosmetic formulations without sedimentation.
Whether you require standard 30% beta-glucan mushroom powder or concentrations up to 80% with low starch percentages, our R&D team can calibrate ratios to meet your project goals.
We provide full dossier support including Certificate of Analysis (CoA), Safety Data Sheets (SDS), allergen statements, GMO-free statements, and botanical origin certification.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
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Continuous innovation guided by scientific principles and social responsibility.
Why Choose Us?
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The factory has passed the China GMP certification.
The EU-GMP and CEP of Ginkgo Biloba Extract has been certificated.
All extraction production lines adopt modern, intelligent and automated control systems.
Own the most advanced extraction equipment in China.
Annual processing of 30,000 tons of Chinese medicine and plant raw materials.
Three annular dynamic countercurrent extraction lines (10t & 15t); two multi-functional extraction lines (32 extraction tanks, 6m³ each); one round dynamic countercurrent extraction line (10t).
Own the only acetone process extraction line for Ginkgo Biloba Extract in China that meets the EU GMP standards.
Own six fermentation tanks (20 tons capacity for each) for the production of enzyme-modified products.
Visualizing our industrial capabilities and manufacturing facility.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system.
With advanced testing instruments, strict control of product quality, to provide every customer with high quality products. Detectable items are: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Important testing instruments are: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, there are two HPLC Shimadzu LC-20AT high performance liquid chromatograph, two HPLC Diane CU3000, two Shimadzu evaporative light scattering detector 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
Quality Control: UniCare’s partners have established complete quality control system. All operations are performed under the guidance of GMP Approved regulations.
| Quality Control Category | Testing Details |
|---|---|
| Active Ingredient Analysis | Assay, identification |
| Hazardous Substance Analysis | Heavy metals, pesticide residue, solvent residue |
| Microbe Analysis | Bacterium, Escherichia coli, Yeast & mould, specific microbial test |
| Raw Material Control | Pesticide residue, allergy origin, GMO, origin of raw material |
| Laws & Regulations Confirmation | Investigation and research of laws and regulations of China and other related countries |
| Stability Test | Guarantee the shelf life according to stability study |
| Others | pH value, moisture, ash, optical rotation, particle size, density, etc. |
◎ The Central Lab is qualified by CNAS.
◎ Professional analysis and important analytical instruments include:
| UHPLC, Agilent 1290 (×2) | HPLC, Agilent (×4) | HPLC, Shimadzu LC-20AT (×2) |
| ELSD, Shimadzu 2000ES (×2) | Shimadzu GC-2010 (×1) | Shimadzu AA-700 (×1) |
Controlling ingredient quality from seed to commercial scale extract.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Essential technical questions answered by our pharmaceutical-grade Quality Assurance department.
Explore our range of dietary supplement and active cosmetic ingredients.
