Global Bulk Botanical Solutions

Wholesale Cranberry Supplier & Factory

Standardized PACs (Proanthocyanidins) and Clean-Label Active Ingredients Engineered for Global Nutraceutical & Functional Food Manufacturers

Market Trends & R&D Insight

The Cranberry Extract Revolution: Standardizing Type-A PACs

Modern urological research and global regulatory shifts are rapidly replacing synthetic treatments with natural prophylactic solutions. Cranberry (Vaccinium macrocarpon) has positioned itself as the gold standard for urinary tract health due to its high density of Type-A Proanthocyanidins (PACs).

Unlike Type-B PACs found in many other plants, Type-A PACs exhibit unique anti-adhesion activities. They bind to the P-fimbriae of uropathogenic Escherichia coli (UPEC), preventing bacterial attachment to the uroepithelial lining. To guarantee clinical efficacy, our advanced extraction facility measures active compounds strictly using the DMAC method, ensuring that every batch delivered contains the exact functional dosage required for health claims.

Botanical laboratory raw materials extraction and testing verification
30,000+
Tons Annual Processing
10%
Net Profit Reinvested in R&D
6
Multi-Functional Extraction Lines
CNAS
Certified Central Laboratory
Corporate Overview

About UniCare

UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.

UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.

UniCare Corporate Laboratory and manufacturing facility

Company Philosophy

Guiding principles driving our pursuit of botanical excellence and sustainable manufacturing.

Value Creation

Discover and create the new value of herb, transforming traditional knowledge into high-purity clinical-grade solutions.

Continuous Improvement

Continuous innovation and improvement across our sourcing, refining, and global logistics networks.

Highest Quality Standards

With the most advanced technology to produce the highest quality products conforming to global pharmacopoeia requirements.

Social Responsibility & Happiness

Make the employees happy and give back to the community, establishing fair trade dynamics with agricultural growers.

Production Infrastructure

Advanced Botanical Extraction System

UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.

Scalable Industrial Output Built for Global Supply Security

Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.

Fully automated botanical extraction lines and control panel

Manufacturing Advantages & Hardware Capability

  • The factory has passed the China GMP certification, adhering to strict regulatory protocols.
  • The EU-GMP and CEP of Ginkgo Biloba Extract has been certificated, meeting strict EU monographs.
  • All extraction production lines adopt modern, intelligent and automated control systems to minimize human error.
  • Own the most advanced extraction equipment in China, optimizing temperature and pressure for delicate active molecules.
  • Annual processing capacity of 30,000 tons of Chinese medicine and plant raw materials.
  • Six production lines: Three annular dynamic countercurrent extraction lines (10 tons & 15 tons); two multi-functional extraction lines (32 extraction tanks with six cubic each); one round dynamic countercurrent extraction line (10 tons).
  • Own the only acetone process extraction line for Ginkgo Biloba Extract in China that meets the EU GMP standards.
  • Own six fermentation tanks (20 tons capacity for each) for the production of enzyme-modified products.

Our GMP Cleanrooms & Extraction Facilities

GMP Plant Facility 1 GMP Plant Facility 2 GMP Plant Facility 3 GMP Plant Facility 4 GMP Plant Facility 5 GMP Plant Facility 6 GMP Plant Facility 7 GMP Plant Facility 8 GMP Plant Facility 9
Analytical Validation

Metrology & Quality Control Systems

United New Life (UniCare) has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products.

HPLC, GC-MS-MS & ICP-MS Detection Capabilities

Detectable items include: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, pH, sulfur dioxide residue, routine detection, etc.

Critical Chromatographic & Spectroscopic Equipment

Important testing instruments include: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, two HPLC Shimadzu LC-20AT high performance liquid chromatographs, two HPLC Dionex CU3000, two Shimadzu evaporative light scattering detector 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.

Quality Control Matrix

Analytical Category Specific Targets & Parameters Evaluated
Active Ingredient Analysis Assay, HPLC / UV chemical identification profiling
Hazardous Substance Analysis Heavy metals, pesticide residue, residual extraction solvents
Microbe Analysis Bacterium count, Escherichia coli, Yeast & mould, specific pathogen testing
Raw Material Control Pesticide residues, allergen screening, non-GMO validation, geographic origin trace
Laws & Regulations Confirmation Regulatory compliance audit under FDA, EFSA, and national regulations
Stability Test Shelf-life evaluation based on accelerated and long-term stability studies
Others pH value, moisture, ash, optical rotation, particle size, bulk density, etc.

Key Analytical Instruments Inventory

UHPLC, Agilent 1290 (×2) HPLC, Agilent (×4) HPLC, Shimadzu LC-20AT (×2)
ELSD, Shimadzu 2000ES (×2) Shimadzu GC-2010 (×1) Shimadzu AA-700 (×1)
Agilent Analytical System in Central Lab HPLC Chromatograph Testing ICP-MS Heavy Metal Testing Setup Gas Chromatograph Setup Analytical Balance and Testing Area
Integrated Supply Chain

Upstream Agronomy & Research Development

From botanical gene optimization to clinical ingredient formulation.

R&D Team analyzing cell structure

Research & Development

UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.

UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.

Raw material planting and agricultural fields

Raw Material Planting & Procurement

In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.

At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.

Macro Enterprise Solutions

Global Enterprise Procurement & Formulation Support

Mitigating supply-chain volatility while maximizing formulation efficacy.

1. Custom Granulation

To suit different packaging standards, we provide customized mesh sizes. From fine soluble powders for instant sachets to direct-compression (DC) granules designed for high-speed tableting and capsule filling without excipient interference.

2. PACs Concentration Tuning

Whether your product matrix requires a standard 1.5% whole fruit powder, a high-potency 25% Proanthocyanidin extract, or clean-label water-soluble derivatives, our engineering team can calibrate chemical concentration profiles.

3. Low-pesticide Clean Label

Through our rigorous quality system and raw material controls, we guarantee that all batches comply with EU Regulation (EC) 396/2005 and EPA standards for pesticide residue thresholds, ensuring seamless custom clearance.

Innovation Roadmap

Technological Roadmap & Future Outlook

Pioneering next-generation bioavailability and biochemical optimization.

Next-Gen Bioavailability Enrichment

In collaboration with top research universities like Beijing University of Chemical Technology, UniCare is investigating enzymatic biotransformation strategies. Our target is to reduce high-molecular-weight polymers into highly bioavailable oligomeric PACs. This will optimize therapeutic absorption rates in the human gut, allowing brands to formulate more effective capsules with smaller dosages.

AI-Driven Crop & Chromatographic Profiling

To counter the climate-driven botanical variations that affect traditional crops, we are building AI-driven liquid chromatography prediction systems. By correlating weather data with HPLC outputs from our planting bases, our system suggests optimal harvesting schedules to ensure consistent concentrations of organic acids and active PACs in the incoming raw berries.

Customer Support Hub

Frequently Asked Questions (FAQ)

Providing transparent, peer-reviewed technical insights for quality assurance managers and procurement directors.

What is the standard measurement protocol used for assaying Cranberry PACs at UniCare?
We offer assay testing through both UV-Vis spectrophotometry (which usually reports higher values due to other polyphenols absorbing light at the same wavelength) and the DMAC (Dimethylaminocinnamaldehyde) method, which is highly specific to Type-A PACs. We advise our B2B customers to state their preferred analysis method (e.g., BL-DMAC, Eur. Ph., or USP) prior to order dispatch so we can calibrate the CoA accordingly.
How does your factory control organic solvents and pesticide residues?
All our manufacturing processes utilize green, eco-friendly solvents (primarily ethanol and purified water). For residue screening, we employ a Shimadzu GC-2010 gas chromatograph and an Agilent 1290 UHPLC paired with mass spectrometry to verify that organochlorines, organophosphates, and heavy metals (lead, arsenic, mercury, cadmium) are well below EFSA (European Food Safety Authority) and FDA regulatory limits.
Can you provide customized particle sizing for specific product configurations?
Yes, our processing lines can accommodate customized milling and mesh sizes (ranging from standard 80 mesh to micro-pulverized 120+ mesh). We also produce direct-compressible (DC) granules designed for high-efficiency capsule filling and tableting operations, complete with stability profiles for the target packaging material.
What quality certifications do your manufacturing partners hold?
Our collaborative facilities operate under complete quality management system certifications, including GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Testing laboratories are calibrated according to CNAS/ISO 17025 standards to ensure traceability and analytical consistency.

Initiate A Technical Sourcing Evaluation

Submit your target active ingredient profile, required testing certifications (e.g., DMAC, HPLC, USP/EP), and monthly volume requirement. Our laboratory managers will prepare a customized proposal and dispatch validation samples within 48 hours.

Contact Our Global Sourcing Office