The global pharmaceutical, nutraceutical, and cosmetic industries are undergoing a massive transition toward plant-derived raw materials. At the center of this botanical revolution sits Sophora japonica L. (syn. Styphnolobium japonicum), commonly known as the Japanese Pagoda Tree. Rich in natural active bioflavonoids such as Rutin (rutoside), Quercetin, Genistein, and Kaempferol, Sophora japonica serves as an essential precursor block for systemic therapeutic applications, vascular health formulas, and cellular anti-aging skincare products.
As leading Sophora japonica plant factories and exporters, we bridge the gap between high-yield agricultural cultivation and scientific purification. Standardizing botanical extractions at an industrial level is critical. High-purity compounds like Rutin NF11 or EP/USP grade Quercetin require precise process controls. We solve major global supply challenges—such as batch variation, heavy metal contaminants, pesticide residues, and supply chain disruptions—by providing vertically integrated supply chain solutions.
Our microcirculation and anti-inflammatory ingredient solutions are engineered for high bioavailability and stability. Through continuous process engineering and biotechnology partnerships, we ensure that bulk supplies of Sophora japonica derivatives meet the highest global pharmacopoeia standards.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Our core competence lies in our scientific approach to botanical verification and manufacturing optimization. By integrating upstream cultivation bases with downstream chromatographic purification, we guarantee that ingredients such as Sophora japonica flower bud extracts consistently hit target concentrations while maintaining undetectable levels of process impurities.
We unlock and cultivate the hidden benefits of medicinal herbs, converting raw biological potential into high-potency ingredients for modern life science applications.
We systematically improve chemical separation and bio-enzymatic conversion technologies, pushing boundaries to elevate industrial yield and extract purity.
We leverage automated, closed-loop extraction machinery and HPLC analysis, ensuring every milligram produced satisfies international quality criteria.
We foster a supportive and rewarding workspace for our teams, while supporting local farming communities via fair-trade, sustainable botanical sourcing.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of raw materials can be processed each year.
This industrial framework enables our Sophora japonica flower bud processing line to operate continuously. Our extraction system uses dynamic countercurrent columns, maintaining constant temperature and vacuum environments. This process preserves the chemical structures of Rutin and Quercetin molecules, preventing thermodegradation and maximizing pure compound recovery.
Our facility operates under rigorous domestic Good Manufacturing Practices, establishing cleanrooms and processing environments matching international pharmaceutical criteria.
We maintain active compliance with EU-GMP and hold a CEP for key botanical products like Ginkgo Biloba Extract, validating our quality control mechanisms for European drug markets.
Our plant incorporates PLC-controlled closed systems for solvent delivery, extraction, concentration, and spray drying, minimizing human error and batch variations.
Equipped with vacuum low-temperature evaporators and membrane filtration systems, we ensure bio-active compound integrity is preserved through every processing stage.
We process vast amounts of plant biomass annually. This scale provides a reliable supply buffer and protects bulk buyers from market shortages.
Featuring 3 annular dynamic countercurrent lines (10t & 15t capacity), 2 multi-functional extraction systems (32 six-cubic-meter tanks), and 1 round dynamic countercurrent line (10t).
The global trade flow of Sophora japonica derivatives is shaped by growing consumer demand for natural cardiovascular support agents. Rutin is an essential compound in pharmaceuticals for venous insufficiency, and Quercetin is a key component in immune-support formulations. Because China provides optimal growing conditions for the Sophora japonica tree, it represents the primary source for over 80% of the world's commercial supply.
Industrial consumers face constant challenges, including shifting raw material costs, changing shipping regulations, and stricter testing for heavy metals and pesticides. Western markets (Europe and North America) have lowered the maximum limit allowed for ethylene oxide (EtO), pyrrolizidine alkaloids (PAs), and synthetic pesticides in herbal extracts.
To address these market requirements, UniCare uses clean extraction methods and monitors raw materials starting at the agricultural phase. Our processing setup uses ethanol-only or water-only extraction processes for our Sophora japonica lines. This helps our clients meet international regulatory criteria and ensures smooth customs clearance.
United New Life (UniCare) has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products.
Our analytical suite is equipped to detect and measure key quality parameters: signature active component verification via HPLC or UV, organic solvent residues using GC, pesticide residues (specifically organochlorine and organophosphorus screenings) via GC-MS/MS, heavy metals (Lead, Arsenic, Mercury, Cadmium, Copper) via ICP-MS, along with microscopic identification, moisture, dry weight loss, total ash, microbial limits, thin layer chromatography (TLC) identification, conductivity, pH, and sulfur dioxide residue levels.
| Quality Control Category | Testing Parameters & Analysis Specifications |
|---|---|
| Active Ingredient Analysis | Assay testing, compound identification, chromatographic profiling (HPLC-DAD, UV-Vis). |
| Hazardous Substance Analysis | Heavy metals profiling, multi-residue pesticide screening (GC-MS/MS), residual solvent testing (GC-FID). |
| Microbe Analysis | Total aerobic microbial count (TAMC), total combined yeast and mold count (TYMC), Escherichia coli, Salmonella, and specific pathogens testing. |
| Raw Material Control | Verification of botanical origin, pesticide residue, allergen sourcing, GMO status, and physical classification of harvest batches. |
| Laws & Regulations Confirmation | Continuous alignment with regulatory standards of China, the EU (European Pharmacopoeia), US FDA (USP), and other target markets. |
| Stability Test | Real-time and accelerated stability studies to guarantee active compound potency over shelf life. |
| Others | Physical property analysis (pH value, moisture content, total ash, optical rotation, bulk/tapped density, particle size analysis). |
Our Central Lab spans a modern workspace and is qualified under CNAS guidelines. Our quality team utilizes high-specification analytical instruments, including:
| UHPLC, Agilent 1290 (×2) | Ultra-High Performance Liquid Chromatography for rapid, high-resolution compound profiling. |
| HPLC, Agilent 1260 (×4) | High Performance Liquid Chromatography sets dedicated to quantitative assay verification of active compounds. |
| HPLC, Shimadzu LC-20AT (×2) | Reliable, high-precision HPLC systems for routine batch analysis and release testing. |
| ELSD, Shimadzu 2000ES (×2) | Evaporative Light Scattering Detectors for compounds lacking strong chromophores. |
| Shimadzu GC-2010 (×1) | Gas Chromatography system specialized in analyzing residual solvents and volatile trace organic substances. |
| Shimadzu AA-7000 (×1) | Atomic Absorption Spectrophotometer for detecting and measuring trace heavy metal quantities. |
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
We maintain deep cooperation with the Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming new raw materials for pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, we have established a comprehensive raw material procurement system. This structure extends procurement tracking directly to individual cultivation plots, enabling batch-level traceablity for our raw materials. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
To ensure consistent quality, UniCare partners with local growers to establish dedicated ginkgo leaf, epimedium, phellodendron, and olive leaf cultivation bases. Several of these bases are managed strictly in accordance with GACP (Good Agricultural and Collection Practices) guidelines.
Additionally, we collaborate with plant genetics researchers to develop high-content seedling varieties. Through traditional hybridization and selection techniques, we target higher active compound yields per hectare. This agricultural focus helps us reduce unit costs and pass those savings on to our industrial clients.
Operating in international markets requires complying with local laws, health standards, and import regulations. Whether you are exporting to the EU, USA, Japan, or South America, having complete compliance documentation is key to maintaining a smooth supply chain.
UniCare provides comprehensive compliance documentation support. We supply complete dossiers including CEP, DMF (Drug Master Files), Certificate of Analysis (CoA), MSDS, allergen statements, GMO-free certifications, and Kosher/Halal approvals.
To support international buyers, we offer localized warehousing solutions and logistics assistance. This helps reduce lead times, simplifies customs clearance, and ensures stable pricing despite fluctuations in international shipping markets.
Purified Rutin and Troxerutin are widely used in pharmaceuticals targeting vascular health. They help support capillary strength and are integrated into prescription treatments for chronic venous insufficiency (CVI), hemorrhoidal disease, and diabetic retinopathy.
Sophora-derived Quercetin is a popular antioxidant in dietary supplements. Formulators combine it with Vitamin C and Zinc to create products focused on seasonal immune support, cardiovascular health, and healthy aging.
With its antioxidant and soothing properties, Sophora japonica extract is an active ingredient in premium cosmetic lines. It helps protect skin cells from UV-induced oxidative stress, helps reduce redness, and supports anti-aging formulations.
The future of phytochemistry relies on cleaner, more selective separation processes. UniCare is transitioning its standard solvent extraction processes toward greener, more sustainable technologies. Our R&D team is refining green extraction processes using Supercritical Carbon Dioxide (scCO2) and Subcritical Water. These technologies help reduce the use of organic solvents, improve safety, and preserve active molecules.
Furthermore, our partnership with the Beijing University of Chemical Technology focuses on enzymatic transformation. By using selective enzymes, we can convert Rutin directly into highly bioavailable Monoglucosyl Rutin and water-soluble Isoquercitrin. This research expands the application possibilities for Sophora japonica derivatives, allowing them to be easily formulated into functional beverages and water-soluble wellness products.
1. Implement green subcritical water extraction systems to phase out traditional organic solvents.
2. Advance enzymatic synthesis of isoquercitrin to improve solubility in aqueous applications.
3. Introduce blockchain-backed agricultural tracing to provide transparent, field-to-bottle records for our clients.
Take a virtual tour of our extraction workshops, fermentation plants, and standard warehousing facilities.
