UniCare is a premier professional developer and manufacturer of natural active ingredients. Catering to global brands across dietary supplements, functional food, cosmetics, and pharmaceuticals, we stand out by bridging upstream botanical cultivation with downstream clinical-grade active constituent delivery. Our development model focuses on product optimization, biological efficacy, and batch-to-batch standardization.
To support demands for robust validation, UniCare works in deep technological alignment with several major Chinese manufacturing entities holding a full suite of management and quality system certifications. These credentials include GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each facility operates a fully independent analytical laboratory equipped with modern chromatographic and spectroscopic technologies, guaranteeing transparency and structural stability for every batch.
In the modern regulatory landscape, sourcing botanical active ingredients has evolved from raw agricultural purchasing to highly complex pharmaceutical and nutraceutical contract development and manufacturing. Organizations are demanding absolute batch-to-batch standardization, complete transparency of origin, and clinical-grade chemical validation. The paradigm shift is driven by consumers who demand "clean label" products free from synthetic additives, combined with strict regulatory verification from bodies such as the FDA, EFSA, and NMPA.
For procurement directors at multinational life sciences brands, selecting a contract manufacturer is no longer just a transaction based on cost per kilogram. It requires evaluating the manufacturer's technological depth. A dependable contract manufacturer must operate as an extension of the brand's scientific integrity, integrating advanced green extraction methods, biotechnology (such as industrial fermentation), and strict analytical verification. As raw material purity standards increase, only suppliers with vertically integrated supply chains and advanced engineering capabilities can maintain regulatory compliance and prevent product recalls.
Global consumer groups and regulatory authorities demand complete traceability, from seed genetics to the final packaged phytochemical powder.
Modern extraction technologies are shifting toward clean solvents, supercritical CO2 extraction, and targeted acetone refinement to eliminate hazardous residual hydrocarbons.
Using enzymatic modification and yeast/bacterial biosynthesis to produce rare bioactive molecules that are difficult or unsustainable to source from nature alone.
UniCare prioritizes production hardware, operating one of the largest and most technologically advanced botanical extraction complexes in China. The entire industrial process is regulated by a centralized, computerized control network that monitors extraction parameters (temperature, pressure, solvent ratios, flow velocities) in real-time, eliminating human error.
Ensuring complete compliance with domestic health, hygiene, and manufacturing protocols.
Holding the industry-standard certification for Ginkgo Biloba extract exports to regulated European territories.
Fully automated extraction processing lines that stabilize active constituent yields and minimize variation between batches.
Using next-generation extraction equipment to isolate precise chemical structures without thermal degradation.
Scale-ready systems designed to process large quantities of raw material and secure global contract supply agreements.
Includes three annular dynamic countercurrent lines (10t & 15t formats), two multi-functional extraction systems (32 vessels at 6m³ capacity each), and one round dynamic countercurrent line (10t).
The only extraction line in China utilizing the clean acetone process for Ginkgo Biloba that meets EU GMP specifications.
20-ton capacity per bioreactor tank, optimized for enzyme-modified products and biosynthesized health ingredients.
Tons Processed / Yr
Extraction Lines
Total Fermentation Vol.
Global supply chain volatility has shown that raw material availability and regulatory compliance are essential for business continuity. China’s Industry 4.0 integration—combining advanced automation, large-scale manufacturing, and digital quality control—helps mitigate these risks. By upgrading production lines from legacy manual operations to automated, closed-loop systems, UniCare helps stabilize active constituent concentration while reducing resource consumption.
This automated infrastructure manages process control with high precision. Thermal control parameters, solvent recycle loops, and vacuum drying profiles are regulated using real-time feedback loops. This technology reduces variability between batches, which is a common challenge with natural plant extracts. Furthermore, by placing manufacturing facilities close to GACP-compliant agricultural centers, we minimize transportation delays, secure our raw material supply, and protect ingredients from natural degradation during transit.
Automated sensors monitor concentration gradients and yield ratios to optimize solvent usage and ensure high extraction efficiency.
Closed-loop solvent recycling systems recover over 95% of process ethanol and acetone, reducing emissions and minimizing manufacturing waste.
Integrating agricultural planting bases with extraction facilities minimizes supply chain risks and insulates production from raw material shortages.
UniCare runs a complete quality control system, validating botanical raw materials, process intermediates, and finished extract profiles in accordance with international standards.
Our analytical laboratories run physical, chemical, and microbiological testing on every production lot. We verify active biomarker profiles via high-performance liquid chromatography (HPLC) and ultraviolet-visible (UV-Vis) spectroscopy. Volatile solvents are analyzed using gas chromatography (GC), and we run multi-residue pesticide analyses using GC-MS-MS. Heavy metal content is monitored using inductively coupled plasma mass spectrometry (ICP-MS), ensuring compliance with international limits for lead, arsenic, mercury, cadmium, and copper.
| Quality Control Category | Testing Metrics & Parameters Evaluated |
|---|---|
| Active Ingredient Analysis | Quantitative HPLC/UV assays, molecular fingerprinting, and botanical identification. |
| Hazardous Substance Analysis | Trace metal evaluation (ICP-MS), organic pesticide residue screens, and residual solvent quantification. |
| Microbiological Profiling | Total aerobic microbial count, yeast and mold quantification, and screening for pathogens (e.g., E. coli, Salmonella). |
| Raw Material Control | Species verification, geographic origin tracing, allergen control, and GMO validation. |
| Regulatory Compliance Validation | Dossier evaluation to match China, US FDA, EU EMA, and other international standards. |
| Stability Studies | Accelerated and long-term shelf-life evaluation under controlled temperature and humidity. |
| Physical Characteristics | Particle size distribution, bulk density, tap density, moisture content, total ash, and pH. |
Our CNAS-qualified central laboratory features specialized analytical instruments for chemical characterization:
| Instrument Classification | Quantity | Analytical Application |
|---|---|---|
| UHPLC Agilent 1290 | 2 Units | Ultra-high performance liquid separation for fast, high-resolution biomarker profiling. |
| HPLC Agilent 1260 | 4 Units | Standard liquid chromatography for quantitative identification of active phytoconstituents. |
| HPLC Shimadzu LC-20AT | 2 Units | Alternative liquid chromatography validation to ensure data accuracy. |
| HPLC Dionex Ultimate 3000 | 2 Units | Automated systems configured for specialized chromatography runs. |
| ELSD Shimadzu 2000ES | 2 Units | Evaporative light scattering detectors, ideal for compounds lacking UV chromophores. |
| Shimadzu GC-2010 | 1 Unit | Gas chromatography for measuring residual solvents and volatile impurities. |
| Shimadzu AA-7000 | 1 Unit | Atomic absorption spectrophotometry for trace heavy metal quantification. |
We reinvest 10% of our annual net profit into research and development. Beyond optimizing existing extraction protocols, our research division targets botanical biotransformation. Our biotechnology department develops enzymatic and microbial fermentation systems to optimize production costs and synthesize complex bioactives.
We maintain an ongoing academic collaboration with the Beijing University of Chemical Technology. This partnership helps bridge the gap between academic biotechnology research and industrial-scale manufacturing, facilitating the transition of new botanical molecules from pilot scale to commercial production.
To control raw material quality at the source, we manage a raw material procurement network that reaches down to individual growing fields. Every batch of raw botanical input is logged, allowing for complete traceback. Storage is maintained under controlled environmental conditions, and raw materials are tested for active compound content, moisture, ash, heavy metals, and pesticide residues before processing.
To secure a reliable supply of key botanicals, UniCare works directly with regional growers to maintain dedicated cultivation bases. This network includes specialized planting bases for Ginkgo Leaf, Epimedium, Phellodendron, and Olive Leaf. Select fields are managed under Good Agricultural and Collection Practices (GACP) protocols. Additionally, we collaborate with plant genetics researchers to breed crop varieties with higher natural concentrations of active compounds, helping lower production costs.
Phytochemical active ingredients require custom physical and chemical profiles to work effectively in different final formulations. A contract manufacturer must provide targeted physical processing to match the specific application:
Optimized for compressibility, low dust, and free-flowing properties, making them suitable for high-speed tableting and capsule filling.
Refined to ensure low odor, consistent color profiles, and clear solubility, making them compatible with emulsions, creams, and water-based serum formulations.
Processed for water solubility, heat stability, and taste masking, allowing for integration into RTD beverages, functional powders, and gummies.
Our partner manufacturing facilities operate under comprehensive global management systems, including GMP, EUGMP, CEP (specifically for Ginkgo Biloba extract), ISO9001, ISO22000, and HACCP. This ensures our processes comply with international standards for food safety, dietary supplements, and pharmaceutical ingredients.
We use a batch numbering system that links each finished product lot back to its specific raw material collection run, including the harvest date and geographic origin. Many of our main ingredients, such as Ginkgo Leaf and Epimedium, are sourced directly from dedicated planting bases managed under GACP (Good Agricultural and Collection Practices) guidelines.
Our facility operates the only acetone-based extraction line for Ginkgo Biloba in China that complies with EU-GMP and CEP requirements. This process efficiently removes unwanted ginkgolic acids while retaining active ginkgo flavone glycosides and terpene lactones, meeting the standards of regulated global pharmacopoeias.
Our CNAS-qualified laboratory tests every batch for contaminants. We analyze heavy metals (lead, mercury, arsenic, cadmium, copper) using ICP-MS, run multi-residue pesticide screens using GC-MS-MS, and measure residual solvents (such as ethanol, acetone, or ethyl acetate) using gas chromatography (GC) to meet global regulatory limits.
Yes. We can modify physical properties like particle size (micronization), bulk density, tap density, and water solubility. For cosmetics, we can adjust color, odor, and stability profiles. For beverage applications, we can optimize ingredients for solubility, clarity, and taste.
