Berberis Aristata, commonly known as Tree Turmeric or Indian Barberry, is an essential medicinal herb historically valued in classical ayurvedic formulations. Today, it has transitioned into a key focus for global pharmaceutical, nutraceutical, and cosmetic manufacturers. The root of Berberis Aristata serves as one of the richest natural sources of Berberine, a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids.
As search intent shifts from generic herbal powders to highly purified, standardized active pharmaceutical ingredients (APIs), global buyers demand verifiable sourcing, analytical transparency, and strict adherence to international regulatory frameworks. China has established itself as the leading hub for high-capacity, advanced extraction technologies, delivering unmatched purity and cost efficiency for Berberis Aristata root derivatives.
Clinical studies highlighting Berberine's efficacy in blood glucose regulation, AMPK activation, and cholesterol management have triggered an exponential surge in international procurement. Brand owners demand standardized Berberine HCl directly from reputable Chinese processing hubs.
Global regulatory bodies like the FDA, EFSA, and EMA enforce strict limitations on pesticide residues, heavy metals, and residual solvents. Ensuring compliance requires robust tracking from wild harvest/GACP farming through advanced GC-MS analysis.
Fluctuating raw material prices demand partner companies with massive processing capacities. With a yearly throughput of 30,000 tons of botanical input, UniCare provides price stability and uninterrupted supply guarantees for multi-year contracts.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Discover and create the new value of herb.
Continuous innovation and improvement.
With the most advanced technology to produce the highest quality products.
Make the employees happy and give back to the community.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system. Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The factory has passed the China GMP certification. All facility guidelines meet or exceed national sanitary standards.
The EU-GMP and CEP of Ginkgo Biloba Extract has been certificated. Our systems adapt dynamically to global drug master files.
All extraction production lines adopt modern, intelligent and automated control systems, minimizing human error and deviation.
Own the most advanced extraction equipment in China, including specialized low-temperature vacuum concentrators.
Annual processing of 30,000 tons of Chinese medicine and plant raw materials, guaranteeing steady B2B supply.
Three annular dynamic countercurrent extraction lines (10t & 15t); two multi-functional extraction lines (32 extraction tanks with six cubic each); one round dynamic countercurrent line (10t).
Own the only acetone process extraction line for Ginkgo Biloba Extract in China that meets the EU GMP standards.
Own six fermentation tanks (20 tons capacity each) for the production of enzyme-modified products and biosynthesized structures.
United New Life has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments, strict control of product quality, to provide every customer with high quality products.
Detectable items include: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
| Quality Control Items | Detailed Testing Parameters & Methodology |
|---|---|
| Active Ingredient Analysis | Assay, chemical profile identification via HPLC, UV, and comparison with USP reference standards. |
| Hazardous Substance Analysis | Heavy metals (Lead, Arsenic, Cadmium, Mercury via ICP-MS), organochlorine pesticide residues, and residual solvents. |
| Microbe Analysis | Total aerobic microbial count, Yeast & mould limits, specific pathogen tests (E. Coli, Salmonella, Staphylococcus aureus). |
| Raw Material Control | Botanical verification, pesticide screens, allergy origin identification, non-GMO assurance, and geographic origin traceability. |
| Laws & Regulations Confirmation | Ongoing alignment of extraction parameters and labeling requirements with EU, FDA, and China Pharmacopeia regulations. |
| Stability Test | Real-time and accelerated stability studies to guarantee long-term shelf life under specific humidity and temperature parameters. |
| Others | pH value, moisture percentage, total ash, optical rotation, bulk density, mesh particle size, and conductivity limits. |
| UHPLC, Agilent 1290 (×2) | Used for high-resolution rapid analysis of active compounds like Berberine HCl. |
| HPLC, Agilent (×4) | Standardized assay controls for multiple botanical streams concurrently. |
| HPLC, Shimadzu LC-20AT (×2) | Routine identification runs and validation of botanical purity levels. |
| ELSD, Shimadzu 2000ES (×2) | Sensing compounds without chromophores (e.g., specific sugars, lipids). |
| Shimadzu GC-2010 (×1) | Critical quantification of residual organic solvents used during extraction. |
| Shimadzu AA-700 (×1) | Atomic absorption spectrophotometry for trace element and heavy metal screening. |
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Global pharmaceutical and nutraceutical manufacturers struggle with the inconsistent concentration of natural Berberine in wild-harvested roots. UniCare resolves this botanical supply challenge with custom, macro-level industry strategies:
We supply Berberis Aristata Root extract standardized to 97%, 98%, and custom 99% Berberine HCl. Buyers can specify particle distribution profiles, from fine powders for compression to granular options for capsules.
Our regulatory team provides comprehensive documentation support, including Drug Master Files (DMF), Certificates of Analysis (CoA), Allergen statements, and Non-GMO certifications for international customs clearance.
Through systematic GACP contract farming and raw material stockpiling, we protect our key clients against volatile market swings, ensuring price lock-ins for extended fiscal cycles.
As industry expectations rise regarding eco-friendly extraction techniques and zero-solvent footprints, UniCare is modernizing its technological framework. We are transitioning our industrial facilities to adopt water-based closed-loop extraction designs. By minimizing alcohol and acetone volumes in secondary purification phases, we align with the global zero-carbon footprint standards mandated by our premier European buyers.
Our ongoing collaboration with Beijing University of Chemical Technology aims to pioneer continuous dynamic extraction processes. This milestone is projected to lower extraction energy consumption by 25% while simultaneously increasing Berberine active compound yields from raw root stocks by 12%.
