Discover our main portfolio of high-purity, bio-optimized plant extracts supplying global healthcare, nutraceutical, and pharmaceutical brands.
As the international dietary supplement and functional food sectors experience an unprecedented shift toward longevity therapeutics and cellular health compounds, flavonoids like Quercetin and Kaempferol have transitioned from simple antioxidant ingredients into highly demanded bio-active agents. Sourced predominantly in China from premium botanical matrices, including Sophora japonica (Linn.) buds, these molecules represent a core chemical pillar for global wellness innovators.
Phytochemical synergy is key. While Quercetin targets senescent cells, improves immune function, and optimizes respiratory pathways through zinc-ionophore properties, Kaempferol complements this activity by modulating cellular transcription factors (Nrf2 and NF-kB) and regulating mitochondrial bioenergetics. Combined, they create a comprehensive cellular defense profile that exhibits higher clinical efficacy than single-compound doses. This synergy has driven key global healthcare conglomerates to seek dual-compound suppliers capable of delivering standardized, high-purity profiles under strict regulation.
B2B buyers face several persistent bottlenecks when sourcing these raw materials: assay variability, heavy metal trace levels, pesticide residue compliance, and solvent residue containment. A professional China Quercetin Kaempferol supplier must offer answers to these points by utilizing validated testing methodologies (such as HPLC-DAD, ICP-MS, and GC-MS-MS) and providing deep traceability documentation from seed selection through to shipping.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
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Driving biotechnology forward with core values centered on scientific integrity, continuous improvement, and environmental responsibility.
Unlocking potential within botanical assets to develop next-generation active ingredients for worldwide health.
Investing heavily in technological evolution, process safety, and high-efficiency purification practices.
Employing state-of-the-art manufacturing mechanisms to ensure strict quality outputs conforming to international guidelines.
Fostering an inclusive workplace environment and implementing eco-friendly supply chain methodologies to benefit society.
Sourcing high-purity Quercetin and Kaempferol from China requires an analytical understanding of the technological pathways deployed during processing. Standardized flavonoid processing has evolved from basic organic solvent extraction to green, high-performance clean systems.
Utilizing food-grade ethanol and pressurized hot water extraction loops to guarantee zero harmful hydrocarbon residues. This ensures compliance with EU Regulation EC 396/2005 on pesticide levels and strict residue limitations.
Developing enzymatic structures that modify flavanoid glycosides (such as rutin and astragalin) into free aglycones (pure Quercetin and Kaempferol), achieving up to 98% purity levels while boosting biological absorption capacities in final product matrices.
Providing modified grades designed for industrial food and functional liquid formulations, overcoming natural hydrophobicity to improve dissolution times and stability under processing temperatures.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
The facility conforms entirely to standard national GMP criteria, ensuring clean process flows.
Certified Ginkgo Biloba Extract production capacity fulfilling strict European standards.
Modernized distributed control system (DCS) for temperature, pressure, and solvent flow control.
Equipped with advanced counter-current extraction tanks and efficient vacuum low-temp concentrators.
Substantial botanical processing capacity ensuring consistent batch sizes and secure contract supplies.
Includes three annular dynamic countercurrent lines (10t & 15t), two multi-functional lines (32 tanks), and one round line.
Houses the only EU-GMP conformant acetone process extraction line for Ginkgo Biloba Extract in China.
Features six 20-ton fermentation tanks for enzymatic transformations and bio-catalyzed product lines.
Hover over the images to inspect our industrial extraction setups, raw material storage, and processing environments.
UniCare has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system.
With advanced testing instruments, strict control of product quality, we provide every customer with high-grade active compounds. Detectable items include: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
Important testing instruments in use: Two UHPLC Agilent 1290 ultra-high performance liquid chromatographs, four HPLC Agilent 1260 high performance liquid chromatography sets, two HPLC Shimadzu LC-20AT high performance liquid chromatographs, two HPLC Dionex UltiMate 3000, two Shimadzu evaporative light scattering detectors (ELSD) 2000ES, one Shimadzu GC2010 gas chromatograph, and one Shimadzu AA-7000 atomic absorption system.
◎ GMP Approved Factory. All operations and management inside the facilities strictly follow GMP regulations.
| Quality Control Items | Detailed Testing Coverage |
|---|---|
| Active Ingredient Analysis | Assay testing, peak area calculation, HPLC identification |
| Hazardous Substance Analysis | Heavy metals (ICP-MS), pesticide residue (GC-MS-MS), residual solvents |
| Microbe Analysis | Total plate count, Escherichia coli, Yeast & mold, specific pathogen tests |
| Raw Material Control | Pesticide residues, allergy origin tracking, GMO status, geographic origin profiling |
| Laws & Regulations Confirmation | In-depth research of regulatory updates in China, US FDA (NDI/GRAS), and EFSA |
| Stability Test | Accelerated and long-term shelf-life validation according to ICH guidelines |
| Physical/Chemical Properties | pH value, moisture, ash, optical rotation, particle size, bulk density |
◎ The Central Lab covers a spacious layout qualified by CNAS standards for third-party validation.
| Analytical Instrument | Quantity & Type |
|---|---|
| UHPLC, Agilent 1290 | 2 units |
| HPLC, Agilent 1260 | 4 units |
| HPLC, Shimadzu LC-20AT | 2 units |
| ELSD, Shimadzu 2000ES | 2 units |
| Gas Chromatograph, Shimadzu GC-2010 | 1 unit |
| Atomic Absorption Spectrophotometer, Shimadzu AA-700 | 1 unit |
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have also established a professional R&D department for the natural fermentation products. By increasing investment in natural fermentation products, we try to break through the traditional processes and disrupt industry development.
UniCare has deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming the new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items of raw materials are strictly controlled.
At the same time, in order to further ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, olive leaf planting bases, etc. Some of these bases are planted strictly in accordance with the GACP management model. In addition, we cooperate with seedling research and development companies to develop high-content seedling cultivation, and cultivate better seedlings through hybridization or gene optimization, so as to continuously reduce unit costs to benefit users.
Operating as a primary supplier for international corporations requires strict compliance with localization rules across major consumer markets. Our logistics and legal departments ensure that every shipment conforms to destination-specific guidelines:
Assisting with FSMA compliance, FDA foreign facility registrations, NDI (New Dietary Ingredient) validation, and providing DSHEA compliant specification sheets. We ensure third-party certifications for Non-GMO Project, Kosher, and Halal remain updated.
Fully compliant with EFSA Novel Food regulations, REACH registration protocols, and European Pharmacopoeia (EP) thresholds for heavy metals, PAHs, and ethylene oxide (ETO) residues. 100% ETO-free product processing guaranteed.
Adhering to China's GB standards, Japan's PMDA positive list system, and Australia's TGA guidelines. Document sets include comprehensive declarations of origin, allergen reports, and BSE/TSE free certification.
Technical and regulatory answers for professional B2B procurement managers and formulation developers.
Discover more high-performance active botanical ingredients developed inside our GMP workshops.
