Wholesale Fermentation Products Factory & Factories

Next-Generation Industrial Bio-Fermentation & Plant-Derived Extraction Solutions

Precision Bio-Fermentation Products

Explore our leading selection of premium bio-synthesized and plant-derived products optimized for global commercial distribution.

Leading the Path in Natural Active Ingredient Bio-Manufacturing

UniCare stands at the forefront of the global life sciences industry as a premier, high-technology supplier of natural active ingredients. Catering to global innovators across the dietary supplement, functional food, cosmetic, and pharmaceutical sectors, we emphasize product development integrity and absolute batch-to-batch quality stability. Our operating model bridges the gap between agricultural sourcing and advanced biotechnology, ensuring a consistent, scalable supply chain for global businesses.

By building strategic, deep alliances with leading Chinese manufacturers, UniCare ensures that our processing facilities operate under the most stringent quality management system certifications. Our partner factories hold globally recognized credentials including GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each facility operates an independent analytical laboratory equipped with high-performance detection instrumentation, validating the high quality and long-term stability of every shipment.

UniCare Scientific Research Facility

Company Philosophy

Merging traditional wisdom with biotechnology to deliver value to the global bio-economy.

Value Creation

Discover and create the new value of herb

Continuous Innovation

Continuous innovation and improvement

Advanced Technology

With the most advanced technology to produce the highest quality products

Social Responsibility

Make the employees happy and give back to the community

Advanced Bio-Production Infrastructure

Our industrial extraction and fermentation facility in China represents the pinnacle of modern manufacturing automation.

Industrial Fermentation Bioreactors

Why Leading Global Brands Partner with UniCare

UniCare integrates industrial infrastructure with precise manufacturing hardware. Operating the largest and most advanced plant extraction and bio-fermentation complex in China, our facilities are monitored by digital control systems. This automation ensures strict compliance with standard operating procedures and minimizes batch-to-batch variability.

The manufacturing complex features two GMP-certified workshops hosting six multi-functional extraction production lines. Among these is China’s exclusive production line for Ginkgo Biloba Extract using a dedicated acetone purification process. This specialized setup processes up to 30,000 tons of raw botanical materials annually, meeting high market demand.

GMP Certification

GMP Certified Processing Facilities

Our operational units adhere to China GMP guidelines, maintaining control standards for cleanrooms, environmental sanitation, and production records.

EU-GMP and CEP

EUGMP & CEP Ginkgo Biloba Production

Our Ginkgo Biloba extract has obtained EU-GMP and CEP certifications, authorizing its usage in international pharmaceutical applications.

Automation Controls

DCS Intelligent Automation Control System

From material loading to purification, the manufacturing line uses automated monitoring systems to regulate temperatures, pressures, and flow rates.

Modern Extraction

Advanced High-Throughput Extraction Plant

Equipped with extraction batteries, filtration centrifuges, and low-temperature vacuum evaporators to prevent thermal degradation of active ingredients.

Annual Processing Capacity

30,000 Tons Annual Biomass Capacity

We process up to 30,000 tons of medicinal herb inputs per year, securing supply stability for high-volume contract buyers.

Extraction Lines

6 Multi-functional Extraction Lines

Consists of 3 annular dynamic countercurrent extraction systems (10 & 15-ton), 2 multi-functional lines (32 x 6m³ tanks), and 1 round dynamic countercurrent line.

Acetone Process

EUGMP Ginkgo Acetone Purification Line

China's singular industrial-scale acetone process extraction line designed to meet international standards for solvent residual control.

Fermentation Bioreactors

Enzyme-Modified Fermentation Capacities

Features 6 specialized, high-capacity fermentation bioreactors (each 20 tons) configured for enzymatically transformed natural compounds.

Production Center & Technology Facilities

An overview of our production halls, extraction systems, and warehousing.

Technological Roadmap & Bio-Fermentation Outlook

Advancing beyond conventional extraction via precision fermentation and synthetic biology platforms.

Transitioning from Extraction to Precision Fermentation

Traditional extraction of phyto-compounds is constrained by agricultural resource availability, environmental conditions, and seasonal active ingredient fluctuations. UniCare is mitigating these limits by engineering advanced enzymatic modification and bio-fermentation pathways to synthesize highly bio-available secondary metabolites.

Our technology roadmap integrates advanced strain development with industrial-scale bioreactor cultivation. By leveraging functional enzymology, we can convert standard plant precursor molecules into higher-value bio-active compounds. This methodology improves molecular purity while eliminating common agricultural pollutants like soil-derived heavy metals and organochlorine pesticide residues.

Furthermore, our ongoing research into synthetic biology platforms aims to transition target compounds toward carbon-neutral biomanufacturing. This reduces water usage, solvent reliance, and environmental impact relative to traditional petrochemical-based organic synthesis.

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Metabolic Engineering & Strain Design

Selecting and optimizing yeast, fungal, or bacterial host organisms to synthesize complex plant metabolites.

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Enzyme Engineering & Biocatalysis

Applying high-selectivity biocatalysts to chemically transform botanical precursors into targeted isomers.

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Scale-Up in 20-Ton Fermentation Bioreactors

Scaling up production parameters to yield high concentrations of clean-label bio-fermented ingredients.

30K+
Tons Annual Biomass Processing
10%
Annual Net Profit Reinvested in R&D
20T
Bioreactor Vessel Capacities
100%
Quality Traceability Verified

Localized Commercial Application Scenarios

Providing customized bio-fermentation and plant extract grades to meet distinct regional and industry specifications.

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Global Pharmaceutical & Nootropic Integrations

Our EU-GMP compliant Ginkgo Biloba extract (acetone process) and ultra-pure Berberine HCl serve as functional active ingredients in neuroprotective formulations. These compounds are engineered to meet European Pharmacopoeia (EP) and United States Pharmacopeia (USP) monographs, supporting clean validation profiles.

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Functional Nutrition & Dietary Supplements

For the North American and EU nutracosmetic markets, we deliver high-potency antioxidants such as Fisetin, Quercetin, and Pomegranate Extract. Our ingredients are refined for optimal bioavailability, supporting applications in capsules, tablets, dry blends, and functional beverages.

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Cosmeceuticals & Dermal Active Agents

In response to clean-label beauty standards in EU and APAC regions, our bio-fermented actives, green tea catechins, and olive-derived polyphenols provide stable, hypoallergenic solutions. They are formulated for compatibility with topical emulsification systems, offering skin barrier support and age-defying activity.

Supply Chain Resilience & Efficiency Advantages

Global raw material procurement requires supply chain resilience. By basing our primary production facilities in China, UniCare capitalizes on deep vertical integration across agricultural farming networks, raw material logistics, and chemical processing infrastructures. This geographical integration guarantees continuous material flow, even amidst fluctuating global trade dynamics.

Our raw material procurement program is designed to trace compounds back to their agricultural origins. We have established dedicated cultivation zones in partnership with local agricultural cooperatives, including ginkgo leaf, epimedium, phellodendron, and olive leaf planting bases. Many of these sites operate in alignment with Good Agricultural and Collection Practices (GACP).

To continuously improve yield efficiency and reduce unit costs, we collaborate with scientific plant-breeding companies. These joint efforts focus on developing optimized botanical cultivars characterized by higher target chemical expression, lowering downstream raw material usage and cost-per-kilogram parameters for our clients.

Botanical Raw Material Harvest

Quality Control System & Testing Rigor

UniCare maintains a comprehensive quality management system, checking raw biomass inputs and finished products for purity and stability.

Our quality assurance program is supported by a CNAS-accredited Central Laboratory. The lab is equipped with advanced testing instrumentation, allowing our team of analytical chemists to perform detailed physical, chemical, and microbiological analyses for every production batch.

Detectable Quality Control Parameters Include: Signature chemical assay (HPLC / UV / GC), solvent residues (GC), pesticide residues (specifically organochlorine pesticides by GC-MS-MS), heavy metals (lead, arsenic, mercury, cadmium, copper by ICP-MS), micro-structural verification, moisture content, loss on drying, ash content, biological limit testing, TLC identification, particle size distribution, bulk density, pH metrics, and sulfur dioxide residue limits.

Analytical Instrument Classification Specific Testing Capacity & Parameters Checked
UHPLC Agilent 1290 (2 Units) Ultra-high-pressure liquid chromatography for precise identification and quantification of target active markers.
HPLC Agilent 1260 (4 Units) Assay testing and verification of complex chemical compositions and marker compounds.
HPLC Shimadzu LC-20AT (2 Units) & Diane CU3000 (2 Units) High-throughput quantitative profiling and verification of organic compounds.
ELSD Shimadzu 2000ES (2 Units) Evaporative light scattering detection for analytes lacking chromophores, such as lipids and sugars.
Shimadzu GC-2010 (1 Unit) Gas chromatography for analyzing volatile organic impurities, residual solvents, and pesticide markers.
Shimadzu AA-7000 (1 Unit) & ICP-MS Atomic absorption and mass spectrometry for detection of trace heavy metals.

Quality Control Parameters Table

Quality Control Items Detailed Testing Parameters & Regulatory Benchmarks
Active Ingredient Analysis Assay, identification, and isomer profiling.
Hazardous Substance Analysis Heavy metals (ICP-MS), pesticide residues, residual solvents (GC).
Microbe Analysis Total plate count, E. coli, Yeast & Mold, Salmonella, and specific pathogens.
Raw Material Control Botanical authentication, GMO verification, allergen screening, and geographical traceability.
Laws & Regulations Confirmation Compliance check against China, FDA (USA), and EFSA (Europe) regulations.
Stability Test Long-term and accelerated stability studies to verify shelf-life parameters.
Others pH value, moisture, ash, optical rotation, particle size distribution, bulk/tapped density.

CNAS Certified Central Laboratory & Analytical Testing Devices

R&D Innovation & Agricultural Integration

Reinvesting in biotechnology to optimize extraction efficiency and agricultural sustainability.

R&D Molecular Engineering

Investment in R&D & Collaborative Partnerships

UniCare reinvests 10% of our annual net profit into our research and development department. This allocation funds both the optimization of our botanical extraction lines and the development of our bio-fermentation technologies.

To support scientific research and development, we maintain a collaborative partnership with the Beijing University of Chemical Technology in the field of fermentation sciences. This partnership bridges academic research and industrial-scale manufacturing, facilitating the commercialization of novel bio-actives for the cosmetic, food, and pharmaceutical industries.

Additionally, our agricultural sourcing model focuses on standardizing raw material inputs. By controlling cultivation conditions at our local growing bases, we manage key parameters including soil mineral balance, natural watering cycles, and harvesting windows. This agricultural control helps minimize variation in raw biomass before it reaches our extraction facilities.

Global Commercial Status & Regulatory Support

Ensuring local compliance and regulatory clearance for international imports.

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Regulatory Clearance & DMF Support

We provide documentation support to facilitate regulatory registration processes. Our compliance team compiles and updates Drug Master Files (DMF), Technical Dossiers, Certificate of Suitability (CEP) records, and detailed Safety Data Sheets (SDS) for our global partners.

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International Supply Logistics

With established distribution logistics, we manage ocean, air, and land freight pathways. Our shipping processes include secure packaging protocols, temperature-monitored shipping options, and customs clearance support to ensure on-time delivery.

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IP Isolation & Clean Manufacturing

For custom synthesis and enzyme-modified products, we maintain strict intellectual property isolation protocols. Our manufacturing runs are managed via campaign-based production schedules, followed by verified equipment cleaning and validation procedures to prevent cross-contamination.

Frequently Asked Questions

Common questions regarding our wholesale manufacturing capacities, testing procedures, and ordering logistics.

What certifications are held by UniCare's partner factories?

Our collaborative production sites maintain certifications for global quality standards, including GMP, EU-GMP, CEP (for Ginkgo Biloba), ISO9001, ISO22000, and HACCP.

How is raw material quality controlled and trace-verified?

We partner with local agricultural cooperatives to establish dedicated cultivation bases (e.g., Ginkgo leaf, Epimedium, Olive leaf) operating under GACP guidelines. Every incoming batch of biomass is tested for identity, purity, heavy metals, and pesticide residues before processing.

What analytical equipment is utilized in your laboratories?

Our CNAS-qualified central laboratory is equipped with advanced analytical instrumentation, including Agilent 1290 UHPLCs, Agilent 1260 HPLCs, Shimadzu GC-2010 systems, and AA-7000 atomic absorption systems.

Can UniCare support custom bio-fermentation scale-up?

Yes. In addition to plant extraction lines, we operate six 20-ton fermentation bioreactors dedicated to enzyme modification and bio-fermentation processes. Through our partnership with Beijing University of Chemical Technology, we assist with scale-up development.

What is the minimum order quantity (MOQ) for industrial orders?

MOQ parameters vary depending on the product classification and customization needs. Standard botanical extracts typically start at 25kg (drum package), while specialized bio-fermented compounds may have custom MOQs.

What is the acetone process extraction used for Ginkgo Biloba?

It is a purification method that meets EU-GMP standards. UniCare partner facilities operate the only industrial-scale acetone process extraction line for Ginkgo Biloba in China, ensuring low solvent residues and a high-purity active profile.

Initiate Your Bio-Fermentation Collaboration Today

Partner with UniCare for high-capacity, certified botanical extracts and advanced bio-fermented active ingredients.

Contact Our Technical Sales Team

Standardized Botanical & Active Ingredients

Our comprehensive portfolio of natural active ingredients, manufactured to meet global regulatory and quality standards.