UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplement, food, cosmetics and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Sophora Root Extract, botanically derived from the roots of Sophora flavescens Aiton (also known in Traditional Chinese Medicine as Ku Shen), represents one of the most therapeutically versatile plant extracts in modern pharmacognosy. Characterized by its rich concentration of quinolizidine alkaloids and prenylated flavonoids, this botanical profile has drawn immense global interest due to its potent anti-inflammatory, antimicrobial, antiviral, and antitumor properties.
At UniCare, as a premier global Wholesale Sophora Root Extract Exporter, we leverage advanced fractional crystallization and chromatographic separation to isolate its primary bio-active markers: Matrine and Oxymatrine. These compounds act as the cornerstone for pharmaceutical formulation, biological agricultural controls, and cosmetic development worldwide.
In highly regulated markets like Europe and North America, purified Matrine and Oxymatrine are investigated for oncology support treatments, anti-arrhythmic formulations, and chronic viral hepatitis therapies. Their ability to induce apoptosis in abnormal cellular configurations without harming healthy somatic tissue makes them a high-value active pharmaceutical ingredient (API).
Sophora root compounds (specifically Kurarinone) act as natural alternatives to hydroquinone for skin-brightening formulations. Additionally, its robust anti-inflammatory capability works exceptionally well in localized topical solutions for eczema, psoriasis, and acne-prone skin profiles, calming redness and reducing sebum hypersecretion.
Global demand for pesticide-free residue crops has positioned Matrine as a premium botanical pesticide. It works through localized contact and stomach poisoning on target pests, particularly affecting their central nervous systems, without posing bioaccumulation threats or toxicity risk to beneficial pollinators like honeybees.
Due to antibiotic restriction directives in livestock feed, agricultural regions use Sophora Root Extract to prevent and treat intestinal infections, coccidiosis, and dysentery in poultry and swine, serving as an effective, natural, non-residual growth promoter.
In wellness markets targeting gut microbiome health, standardized Sophora Root Extracts are formulated into capsules aimed at balancing intestinal flora and reducing systemic oxidative stress, promoting long-term immunological resilience.
As the regulatory landscap around synthetic chemical additives tightens, natural botanicals must step up in consistency, purity, and environmental sustainability. UniCare, along with our leading academic partners, has laid down a comprehensive technical roadmap designed to guarantee our place as a pioneering global exporter for the next decade.
Traditional extraction relies heavily on ethanol-water or organic matrices. Our R&D works on implementing Supercritical Carbon Dioxide (SFE-CO2) and Subcritical Water Extraction (SWE). These methods ensure that no residual organic solvents remain in the end product, significantly increasing the safety and efficacy profile for baby care cosmetics and high-grade clinical APIs.
Collaborating with the Beijing University of Chemical Technology, we explore metabolic engineering pathways. By utilizing specific natural enzymes within our dedicated fermentation facilities, we can convert low-yield alkaloids into high-demand Matrine and Oxymatrine variants, reducing the ecological footprint of raw biomass harvesting while stabilizing raw material supply dynamics.
We are advancing our agricultural programs to isolate cultivars of Sophora flavescens with naturally elevated alkaloid percentages. Utilizing hybridization and non-GMO gene optimization in breeding nurseries, we aim to double the yield of matrine per hectare, driving down production costs to transfer monetary value back to our global clients.
Unlocking botanical mysteries via molecular isolation to serve modern therapeutic demands globally.
Redesigning extraction systems and upgrading analytical precision to stay ahead of international guidelines.
Fusing intelligent process automation with clinical-grade validation for peak reliability.
Promoting sustainable farming partnerships that boost rural community economies while retaining ecological diversity.
Our supply chain robustness is driven by owning and partnering with the largest and most advanced botanical extraction factory infrastructure in China. UniCare handles manufacturing processes through intelligent, automated control software that continuously registers heat, solvent cycles, pressure gradients, and yield calculations.
With an annual processing potential exceeding 30,000 tons of Chinese medicine and raw botanical resources, we provide consistent supply guarantees despite raw ingredient shortages or market spikes. In addition, we host 6 dedicated extraction loops including three annular dynamic countercurrent setups (10 & 15 tons), two multi-functional structures, and one round dynamic layout.
We boast the only acetone process extraction system for Ginkgo Biloba Extract in China that fully complies with EU GMP norms, indicating our capability to design clean chemical pathways across our entire herbal catalog, including Sophora Root formulations.
The manufacturing complex is constructed under strict national China GMP standards and audited to meet international standards.
Our Ginkgo Biloba line is EU-GMP and CEP certified, highlighting our commitment to quality across all lines.
Entire manufacturing routes utilize automated DCS monitoring networks for consistent output.
Equipped with state-of-the-art countercurrent extractors, low-temperature evaporators, and spray drying systems.
High capacity ensures steady pricing and bulk supply contracts for international buyers.
Six large-scale lines, including three 10-15 ton dynamic countercurrent systems for maximum yield.
Operating advanced chemical processes (like the acetone system) to meet European pharmacopoeia requirements.
Six 20-ton fermentation tanks support biotech modification and enzyme-based product synthesis.
UniCare maintains a comprehensive quality control system, validating botanical composition, chemical stability, and purity limits from raw materials to final packaging.
| Analytical Category | Monitored Quality Parameters | Advanced Diagnostic Methodology |
|---|---|---|
| Active Marker Quantification | Matrine Assay, Oxymatrine Assay, Sophocarpine levels | Ultra-High Performance Liquid Chromatography (UHPLC-DAD/Agilent 1290), HPLC-ELSD |
| Solvent Residue Profiling | Ethanol, Acetone, Hexane, Ethyl Acetate residues | Headspace Gas Chromatography with Flame Ionization Detection (HS-GC-FID / Shimadzu GC-2010) |
| Heavy Metal Limits | Lead (Pb), Arsenic (As), Cadmium (Cd), Mercury (Hg), Copper (Cu) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Atomic Absorption (Shimadzu AA-700) |
| Pesticide Residue Screening | Organochlorines, Organophosphates, Pyrethroids (over 300 target compounds) | Triple Quadrupole Gas Chromatography-Mass Spectrometry (GC-MS-MS / LC-MS-MS) |
| Microbiological Evaluation | Total Aerobic Microbial Count (TAMC), Yeast & Mold, E. coli, Salmonella, Staphylococcus | USP / EP microbiological testing methods within our CNAS-qualified central lab |
| Physical Characteristics | Bulk Density, Tap Density, Particle size distribution, Loss on drying, Ash contents | Laser diffraction sizing, halogen moisture analysis, muffle furnace gravimetric ash analysis |
UniCare invests 10% of our annual net profit back into scientific research and development. Beyond perfecting traditional physical extraction routes, our specialist researchers focus on biological fermentation applications. By using custom microbial pathways to modify molecules, we develop products that help optimize raw material performance for our clients.
We work in deep scientific collaboration with the Beijing University of Chemical Technology, developing and validating next-generation pharmaceutical, cosmetic, and wellness compounds from pilot scale to mass output.
To control trace contaminants and ensure compound yield, we manage a sourcing tracking protocol that covers every harvest batch back to its original farm coordinates. Storage runs under GMP-compliant environments monitoring heat and relative humidity.
To secure reliable raw material supply, we partner with agricultural farms to manage dedicated, traceable planting bases for Ginkgo Leaf, Epimedium, Phellodendron, and Olive Leaf. Select locations run under strict GACP (Good Agricultural and Collection Practices) models. We also work with botanical nurseries to isolate high-yield seedlings through hybridization and natural selection, working to lower costs and pass savings to our customers.
