Discover our highly standardized natural active ingredients, meticulously manufactured for dietary supplements, functional foods, and pharmaceutical formulations worldwide.
In the wake of tightening public health regulations, sugar taxes, and a shift in consumer consciousness toward metabolic health, food and beverage giants are aggressively reforming their recipes. The global sweetener landscape has undergone a monumental shift from chemical synthetics (such as aspartame, acesulfame-K, and sucralose) to high-performance, natural, plant-based molecules. Central to this paradigm shift is Stevia Extract, a zero-calorie sweetener derived from the leaves of the Stevia rebaudiana plant.
However, formulating with stevia extract presents deep organoleptic and biochemical challenges. The native stevia leaf contains a cocktail of sweet glycosides alongside minor compounds that trigger off-notes, such as bitterness and a lingering licorice-like aftertaste. Today's global manufacturers and exporters are no longer merely shipping crude stevia powders; instead, they are deploying high-resolution chromatographic purification, enzymatic modification, and molecular breeding to unlock clean-tasting, premium steviol glycosides like Rebaudioside M (Reb M), Rebaudioside D (Reb D), and customized Reb A blends.
As a senior B2B ingredient supplier, UniCare stands at the intersection of agricultural sustainability and advanced bioseparation. This comprehensive guide outlines the macro solutions, manufacturing parameters, global compliance pathways, and biotechnology roadmaps that define modern wholesale stevia procurement.
Ideal for diabetic formulations, metabolic health products, and keto-friendly food systems. Yields clean sweetness with zero insulinogenic response.
Maintains structural integrity up to 200°C and across a pH range of 2.0 to 10.0, rendering it highly stable in pasteurized beverages, baked goods, and dairy products.
Recognized globally as a natural plant extract, bypassing the stringent regulatory warnings associated with synthetic artificial sweeteners in global markets.
Industrial procurement goes beyond transactional pricing. Today's FMCG leaders demand complete transparency, organoleptic perfection, and flawless supply chain logistics.
Pure Rebaudioside A (Reb A) at high concentrations (e.g., Reb A 97%, 98%) exhibits a distinct bitter profile due to its interaction with the TAS2R4 and TAS2R38 bitter taste receptors on the human tongue. Global food formulators require sophisticated sweetening systems.
UniCare works closely with developers to deliver proprietary ratios of Reb A + Reb D + Reb M. By blending minor glycosides, we achieve a rapid-onset, rounded sweetness curve that closely mimics sucrose, eliminating the need for expensive taste-masking agents.
Stevia leaves are prone to accumulating pesticide residues and heavy metals from agricultural soils. Large-scale global importers require absolute compliance with US EPA, FDA, and European Food Safety Authority (EFSA) maximum residue limits (MRLs).
Through our GACP-compliant (Good Agricultural and Collection Practices) cultivation bases, we ensure seed-to-shelf traceability. Every batch of UniCare stevia extract undergoes validation via high-resolution Gas Chromatography-Mass Spectrometry (GC-MS-MS) and ICP-MS for heavy metals.
UniCare is a professional supplier of natural active ingredients. Our products are widely used in various fields such as dietary supplements, food, cosmetics, and pharmaceuticals. We focus on product development and quality stability, and insist on growing together with our customers around the world.
UniCare has established deep cooperation with several excellent Chinese manufacturers who have complete quality management system certifications, including but not limited to GMP, EUGMP, CEP, ISO9001, ISO22000, and HACCP. Each factory has independent testing capabilities and is equipped with advanced and efficient testing equipment to ensure the high quality and long-term stability of each batch of products.
Guiding principles driving our technological research and commitment to sustainable global health.
State-of-the-art engineering driving natural extract processing at a massive scale.
UniCare attaches great importance to the hardware conditions of production equipment and has the largest and most advanced extraction factory in China. The entire production line in UniCare is controlled by a modern, intelligent, automatic control system.
Until now, UniCare has built up two GMP workshops, containing six multi-functional extraction lines, among which there is the only production line for Ginkgo Biloba Extract of acetone process in the whole China. Here are several other production lines including fermentation production lines and Chinese medicine pieces. A total of 30,000 tons of various Chinese medicine plant raw materials can be processed each year.
Ensuring compliance with rigorous national pharmaceutical and dietary supplement standards.
Fully compliant with European Pharmacopoeia and international pharmaceutical directives.
All extraction lines adopt advanced DCS automated systems for batch-to-batch stability.
Equipped with China's most advanced solid-liquid extraction and purification infrastructure.
Robust raw material processing capabilities ensuring continuity of supply.
Includes dynamic countercurrent extraction lines & multi-functional extraction tanks.
Owns the only acetone process extraction line for Ginkgo Biloba in China meeting EU GMP standards.
Six 20-ton fermentation tanks dedicated to the production of enzyme-modified products.
A glimpse inside our modern manufacturing workshops, sterile packaging cleanrooms, and testing facilities.










Absolute validation of raw materials, process parameters, and finished goods to meet global regulatory limits.
UniCare has established a leading and complete quality control system, and strictly controls the high quality of products in accordance with the quality system. With advanced testing instruments and strict control of product quality, we provide every customer with high quality products.
Detectable items include: Signature component detection (HPLC or UV), solvent residues GC, pesticide residues (organochlorine detection) GC-MS-MS, heavy metals (lead, arsenic, mercury, cadmium, copper) ICP-MS microscopic identification, moisture, dry weight loss, ash, microbial limits, thin layer identification, weighing, conductivity, PH, sulfur dioxide residue, routine detection, etc.
| Testing Domain | Specific Testing & Analytical Parameters |
|---|---|
| Active Ingredient Analysis | Assay determination, chromatogram identification, impurities monitoring |
| Hazardous Substance Analysis | Heavy metals profiling (ICP-MS), pesticide residue (GC-MS-MS), solvent residues (GC-FID) |
| Microbe Analysis | Total aerobic microbial count (TAMC), Escherichia coli, Yeast & mould (TYMC), specific pathogen tests |
| Raw Material Control | Pesticide residues screening, allergen screening, Non-GMO verification, botanical origin authentication |
| Laws & Regulations Confirmation | Investigation and alignment with China GB, US FDA (GRAS), EU EFSA, and regional food additive laws |
| Stability Test | Real-time and accelerated stability chamber testing to validate shelf-life parameters |
| Physical/Chemical Diagnostics | pH value, moisture content, total ash, optical rotation, particle size distribution, bulk density, etc. |
The Central Lab spans a massive footprint, fully qualified by CNAS (China National Accreditation Service for Conformity Assessment). Key instrumentation includes:
| Instrument Type | Configuration & Model Details |
|---|---|
| Ultra-High Performance Liquid Chromatography (UHPLC) | Two UHPLC Agilent 1290 systems for ultra-fast, high-resolution compound profiling |
| High Performance Liquid Chromatography (HPLC) | Four Agilent 1260 HPLC systems, two Shimadzu LC-20AT systems, two Dionex Ultimate 3000 systems |
| Evaporative Light Scattering Detector (ELSD) | Two Shimadzu 2000ES ELSD systems for non-chromophoric compound detection |
| Gas Chromatography (GC) | One Shimadzu GC-2010 gas chromatograph for organic volatile impurities & solvents |
| Atomic Absorption Spectroscopy (AAS) & ICP-MS | One Shimadzu AA-7000 atomic absorption system for heavy metal profiling |
Upstream agricultural control and continuous bio-catalytic research to optimize natural sweetness.
UniCare invests 10% of our annual net profit in research and development. In addition to optimizing and developing the existing natural plant extraction process, we have established a professional R&D department for natural fermentation products. By increasing investment in natural fermentation products, we try to break through traditional processes and disrupt industry development.
UniCare maintains deep cooperation with Beijing University of Chemical Technology in the field of fermentation, jointly developing and transforming new raw materials of pharmaceutical, cosmetic, and natural health products into mass-produced products.
In order to control raw materials more efficiently and with higher quality, a raw material procurement system has been established, which extends procurement to every piece of planting land and can trace the raw materials of each batch of products. The storage of raw materials is operated according to the advanced quality management system process, and the content of active ingredients, moisture, ash, heavy metals, pesticide residues and other items are strictly controlled.
At the same time, to ensure the high quality of important products, UniCare cooperated with planting farmers to establish ginkgo leaf planting bases, epimedium planting bases, phellodendron planting bases, and olive leaf planting bases. Some of these bases are managed strictly in accordance with the GACP model. In addition, we cooperate with seedling research and development companies to cultivate better seedlings through hybridization or gene optimization, continuously reducing unit costs for users.
How UniCare helps developers integrate steviol glycosides into complex matrix formulations.
Carbonated drinks, fruit juices, and RTD teas benefit from Reb M and Reb D blends. Our solutions deliver rapid sweetness without masking delicate acidic or fruity notes, ensuring a clean finish without lingering bitterness.
Yogurt, flavored milks, and oat/almond alternatives require stable sweetness that survives pasteurization. Our stevia components align with dairy proteins and starches without causing flavor suppression or syneresis.
Replacing bulk sugar in baked goods requires combining stevia with polyols (like Erythritol) or soluble fibers. We provide customized co-spray-dried systems that match the volume, browning properties, and sweetness of sucrose.
The future of stevia extends beyond simple leaf extraction. As demand for rare glycosides like Reb M and Reb D grows, standard extraction from traditional stevia leaves is limited by low natural concentrations (often less than 1% of the leaf dry weight). This makes large-scale extraction cost-prohibitive. To overcome this limitation, the industry is transitioning toward two main advanced platforms:
In partnership with university laboratories and biotechnology centers, UniCare is actively researching biotransformation pathways. Our goal is to expand the availability of next-generation clean-label sweeteners, offering cost-effective and sustainable alternatives to global manufacturers.
Expert technical answers for procurement officers, R&D chemists, and global distributors.
Standardized herbal extracts produced under strict GMP control systems to support global health industries.